Evidence map›Paper›PMID 41827846›Full record

ArticleCells2026

A Novel Competing Endogenous RNA Linked to Dysregulated Neuroinflammation in Alzheimer's Disease.

Dinesh Devadoss, Juliet Akkaoui, Natalia Orso, Thiruselvam Viswanathan, Glen M Borchert, Madepalli K Lakshmana, Hitendra S Chand

Abstract read
In one paragraph

Article in Cells, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Dinesh DevadossDepartment of Cellular and Molecular Medicine, Herbert Wertheim College of Medicine, Florida International University, Miami, FL 33199, USA.ORCID 0000-0003-0069-1799
Juliet AkkaouiDepartment of Cellular and Molecular Medicine, Herbert Wertheim College of Medicine, Florida International University, Miami, FL 33199, USA.ORCID 0000-0003-1716-4928
Natalia OrsoDepartment of Cellular and Molecular Medicine, Herbert Wertheim College of Medicine, Florida International University, Miami, FL 33199, USA.
Thiruselvam ViswanathanDepartment of Cellular and Molecular Medicine, Herbert Wertheim College of Medicine, Florida International University, Miami, FL 33199, USA.
Glen M BorchertDepartment of Pharmacology, University of South Alabama, Mobile, AL 36688, USA.ORCID 0000-0002-6182-7154
Madepalli K LakshmanaDepartment of Cellular and Molecular Medicine, Herbert Wertheim College of Medicine, Florida International University, Miami, FL 33199, USA.
Hitendra S ChandDepartment of Cellular and Molecular Medicine, Herbert Wertheim College of Medicine, Florida International University, Miami, FL 33199, USA.ORCID 0000-0002-0574-9307

Funding

National Institute of Allergy and Infectious Diseases R21AI152937NIA NIH HHS 3R21AI152937-02S1
6 · The paper itself

Abstract

Alzheimer's disease (AD) is an aging-associated neurodegenerative disorder in which dysregulated neuroinflammation drives disease progression. Although long noncoding RNAs (lncRNAs) are increasingly implicated in AD, their mechanistic roles remain poorly defined. Here, we identified a novel lncRNA termed

Indexed as

Alzheimer DiseaseInflammationNeuroinflammatory DiseasesRNA, Competitive EndogenousRNA, Long NoncodingAmyloid beta-Protein PrecursorAnimalsAstrocytesBrainDisease Models, AnimalHumansMiceMice, TransgenicMicrogliaMicroRNAsAmyloid beta-Protein PrecursorMicroRNAsRNA, Competitive EndogenousRNA, Long NoncodingAlzheimer’s disease (AD)competing endogenous RNA (ceRNA)long noncoding RNAs (lncRNAs)microRNAs (miRNAs)neuroinflammation

Identifiers

PMID41827846
PMCPMC12984200

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.