ArticleCancers2026
Acute Toxicities During Proton Therapy with or Without Simultaneous Chemotherapy in Pediatric CNS Tumors: A Retrospective Cohort Study.
Eicke Schuermann, Sarah Peters, Jonas E Adolph, Julien Merta, Stefan Rutkowski, Michael C Frühwald, Philipp Dammann, Hermann L Müller, Christof M Kramm, Gudrun Fleischhack and 2 more
Abstract read
In one paragraphArticle in Cancers, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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1 · What the graph read from itWhat it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
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3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
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4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
12 authors.
Eicke SchuermannDepartment of Pediatrics III, Center for Translational Neuro- and Behavioral Sciences (CTNBS), University Hospital of Essen, 45122 Essen, Germany.
Sarah PetersWest German Proton Therapy Center Essen (WPE), University Hospital Essen, 45122 Essen, Germany.
Jonas E AdolphDepartment of Pediatrics III, Center for Translational Neuro- and Behavioral Sciences (CTNBS), University Hospital of Essen, 45122 Essen, Germany.ORCID 0000-0003-4446-8257 Julien MertaWest German Proton Therapy Center Essen (WPE), University Hospital Essen, 45122 Essen, Germany.
Stefan RutkowskiDepartment of Pediatric Hematology and Oncology, Center for Obstetrics and Pediatrics, University Medical Center Hamburg-Eppendorf, 20251 Hamburg, Germany.
Michael C FrühwaldSwabian Children's Cancer Center, Pediatric and Adolescent Medicine, Faculty of Medicine, University Augsburg, 86156 Augsburg, Germany.ORCID 0000-0002-8237-1854 Philipp DammannDepartment of Neurosurgery and Spine Surgery, University Hospital Essen, 45122 Essen, Germany.
Hermann L MüllerDepartment of Pediatrics and Pediatric Hematology/Oncology, University Children's Hospital, Klinikum Oldenburg AöR, 26133 Oldenburg, Germany.
Christof M KrammDepartment of Child and Adolescent Health, Division of Pediatric Hematology and Oncology, University Medical Center Göttingen, 37075 Göttingen, Germany.ORCID 0000-0002-5017-926X Gudrun FleischhackDepartment of Pediatrics III, Center for Translational Neuro- and Behavioral Sciences (CTNBS), University Hospital of Essen, 45122 Essen, Germany.ORCID 0000-0001-5714-007X Beate TimmermannWest German Proton Therapy Center Essen (WPE), University Hospital Essen, 45122 Essen, Germany.ORCID 0000-0003-2274-2008 Stephan TippeltDepartment of Pediatrics III, Center for Translational Neuro- and Behavioral Sciences (CTNBS), University Hospital of Essen, 45122 Essen, Germany.ORCID 0000-0001-8791-9914 Funding
Deutsche Kinderkrebsstiftung, German Children Cancer Foundation DKS 2013.01, DKS 2014.01, DKS 2015.20
6 · The paper itselfAbstract
PubMed holds no abstract for this paper.
Indexed as
adolescentschildrenCNS tumorshigh grade adverse eventsproton beam therapysafetysimultaneous radiochemotherapy
Identifiers
PMID41827792
PMCPMC12984774
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