Evidence map›Paper›PMID 41827780›Full record

ArticleCancers2026

Modulation of Leukemic Blasts into Dendritic Cells (DC

Daniel Christoph Amberger, Zuzana Fischer, Diana Deen, Anika Hirn-Lopez, Caroline Plett, Alexander Rabe, Christoph Schwepcke, Selda Ugur, Lara Kristina Klauer, Christian Ansprenger and 4 more

Abstract read
In one paragraph

Article in Cancers, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Daniel Christoph AmbergerDepartment of Medicine III, University Hospital of Ludwig-Maximilian-University Munich, 81377 Munich, Germany.ORCID 0000-0002-5331-0884
Zuzana FischerDepartment of Medicine III, University Hospital of Ludwig-Maximilian-University Munich, 81377 Munich, Germany.
Diana DeenDepartment of Medicine III, University Hospital of Ludwig-Maximilian-University Munich, 81377 Munich, Germany.
Anika Hirn-LopezDepartment of Medicine III, University Hospital of Ludwig-Maximilian-University Munich, 81377 Munich, Germany.
Caroline PlettDepartment of Medicine III, University Hospital of Ludwig-Maximilian-University Munich, 81377 Munich, Germany.
Alexander RabeDepartment of Medicine III, University Hospital of Ludwig-Maximilian-University Munich, 81377 Munich, Germany.
Christoph SchwepckeDepartment of Medicine III, University Hospital of Ludwig-Maximilian-University Munich, 81377 Munich, Germany.
Selda UgurDepartment of Medicine III, University Hospital of Ludwig-Maximilian-University Munich, 81377 Munich, Germany.
Lara Kristina KlauerDepartment of Medicine III, University Hospital of Ludwig-Maximilian-University Munich, 81377 Munich, Germany.ORCID 0000-0002-8560-7447
Christian AnsprengerDepartment of Medicine III, University Hospital of Ludwig-Maximilian-University Munich, 81377 Munich, Germany.
Anja LiepertDepartment of Medicine III, University Hospital of Ludwig-Maximilian-University Munich, 81377 Munich, Germany.
Markus FreudenreichDepartment of Medicine III, University Hospital of Ludwig-Maximilian-University Munich, 81377 Munich, Germany.
Christoph SchmidBavarian Cancer Research Center (BZKF), 80539 Munich, Germany.
Helga Maria SchmetzerDepartment of Medicine III, University Hospital of Ludwig-Maximilian-University Munich, 81377 Munich, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

objectivesAcute myeloid leukemia (AML) is characterized by impaired anti-leukemic immune responses, and the ex vivo or in vivo generation of dendritic cells (DCs), including leukemic dendritic cells (DC

methodsThis study examined the generation, phenotype and functional relevance of DCs and DC

resultsWe show that DC/DC

conclusionsThese findings identify phenotypic and functional immune parameters as predictors of clinical outcome and highlight the prognostic relevance of ex vivo immune profiling. This approach may help to optimize and personalize future immunotherapeutic strategies in AML.

Indexed as

AMLanti-leukaemic activityDC/DCleu-generating protocolsleukaemia-derived dendritic cells

Identifiers

PMID41827780
PMCPMC12984686

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.