Evidence map›Paper›PMID 41827365›Full record

ReviewJournal of clinical medicine2026

Preeclampsia: Contemporary Concepts in Pathophysiology, Risk Stratification, Prevention and Monitoring.

Piotr Witkowski, Bartosz Dzieński, Katarzyna Stefańska, Martyna Tomaszewicz, Magdalena Zabielska-Kaczorowska, Dariusz Wydra

Abstract readReview
In one paragraph

Review in Journal of clinical medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Piotr WitkowskiDepartment of Gynecology and Obstetrics, Medical University of Gdańsk, Mariana Smoluchowskiego 17, 80-214 Gdansk, Poland.
Bartosz DzieńskiDepartment of Gynecology and Obstetrics, Medical University of Gdańsk, Mariana Smoluchowskiego 17, 80-214 Gdansk, Poland.
Katarzyna StefańskaDepartment of Gynecology and Obstetrics, Medical University of Gdańsk, Mariana Smoluchowskiego 17, 80-214 Gdansk, Poland.
Martyna TomaszewiczDepartment of Medical Immunology, Medical University of Gdańsk, Dębinki 7, 80-211 Gdansk, Poland.ORCID 0000-0001-5702-1580
Magdalena Zabielska-KaczorowskaDepartment of Physiology, Medical University of Gdańsk, Dębinki 1, 80-211 Gdansk, Poland.
Dariusz WydraDepartment of Gynecology and Obstetrics, Medical University of Gdańsk, Mariana Smoluchowskiego 17, 80-214 Gdansk, Poland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Preeclampsia is a heterogeneous disorder affecting approximately 2-5% of pregnancies and remains a major cause of maternal and perinatal morbidity and mortality worldwide. Its clinical presentation ranges from mild, nearly asymptomatic forms to severe conditions progressing to eclampsia or HELLP syndrome. Despite significant advances in understanding its pathophysiology, preeclampsia continues to pose diagnostic and therapeutic challenges. In recent years, intensive research efforts have focused on developing comprehensive diagnostic criteria, identifying novel biomarkers, improving risk prediction models, and establishing effective preventive and monitoring strategies. However, expert opinions and clinical guidelines remain partially inconsistent. This review aims to summarize current global concepts regarding the epidemiology, pathophysiology, risk stratification, diagnosis, prevention, and monitoring of preeclampsia, with particular emphasis on emerging biomarkers and personalized approaches to patient care.

Indexed as

angiogenic imbalancegestational hypertensionHELLPpathophysiology of preeclampsiaprevention strategiesproteinuriasFlt-1/PIGF ratio

Identifiers

PMID41827365
PMCPMC12985448

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.