Evidence map›Paper›PMID 41827270›Full record

ReviewJournal of clinical medicine2026

Endovascular Creation of Native Arteriovenous Fistulas for Hemodialysis: A Percutaneous, Vessel-Sparing Strategy for Vascular Access.

Giulio Distefano, Alessio Sturiale, Concetto Sessa, Ivana Maria Grazia Alessandrello, Andrea Boncoraglio, Elisa Cicero, Dario Galeano, Roberta Maria Messina, Vincenzo Ficara, Fiorenza Rauseo and 6 more

Abstract readReview
In one paragraph

Review in Journal of clinical medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Giulio DistefanoInstitute of Nephrology and Dialysis, Maggiore Hospital of Modica, ASP Ragusa, 97100 Ragusa, Italy.ORCID 0000-0003-0735-5720
Alessio SturialeInstitute of Nephrology and Dialysis, Maggiore Hospital of Modica, ASP Ragusa, 97100 Ragusa, Italy.
Concetto SessaInstitute of Nephrology and Dialysis, Maggiore Hospital of Modica, ASP Ragusa, 97100 Ragusa, Italy.
Ivana Maria Grazia AlessandrelloInstitute of Nephrology and Dialysis, Maggiore Hospital of Modica, ASP Ragusa, 97100 Ragusa, Italy.
Andrea BoncoraglioRadiology Unit, Giovanni Paolo II Hospital, ASP Ragusa, 97100 Ragusa, Italy.ORCID 0000-0002-0251-1133
Elisa CiceroInstitute of Nephrology and Dialysis, Maggiore Hospital of Modica, ASP Ragusa, 97100 Ragusa, Italy.
Dario GaleanoInstitute of Nephrology and Dialysis, Maggiore Hospital of Modica, ASP Ragusa, 97100 Ragusa, Italy.
Roberta Maria MessinaInstitute of Nephrology and Dialysis, Maggiore Hospital of Modica, ASP Ragusa, 97100 Ragusa, Italy.
Vincenzo FicaraInstitute of Nephrology and Dialysis, Maggiore Hospital of Modica, ASP Ragusa, 97100 Ragusa, Italy.
Fiorenza RauseoInstitute of Nephrology and Dialysis, Maggiore Hospital of Modica, ASP Ragusa, 97100 Ragusa, Italy.
Alessia TiganoInstitute of Nephrology and Dialysis, Maggiore Hospital of Modica, ASP Ragusa, 97100 Ragusa, Italy.
Viviana ScolloInstitute of Nephrology and Dialysis, Maggiore Hospital of Modica, ASP Ragusa, 97100 Ragusa, Italy.
Fortunata ZirinoInstitute of Nephrology and Dialysis, Maggiore Hospital of Modica, ASP Ragusa, 97100 Ragusa, Italy.
Carmelo ZuppardoInstitute of Nephrology and Dialysis, Maggiore Hospital of Modica, ASP Ragusa, 97100 Ragusa, Italy.
Domenico PatanèDepartment of Radiology, Azienda Ospedaliera Cannizzaro, 95021 Catania, Italy.
Walter MoraleInstitute of Nephrology and Dialysis, Maggiore Hospital of Modica, ASP Ragusa, 97100 Ragusa, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Surgically created native arteriovenous fistulas (AVFs) remain the preferred vascular access for chronic hemodialysis, yet they are limited by substantial early failure and progressive consumption of venous capital. Endovascular arteriovenous fistulas (endoAVFs, also referred to as percutaneous AVFs) have become a catheter-based alternative to surgical AVF (sAVF). We conduct an updated narrative, practice-oriented review of the literature on endoAVF creation, and we qualitatively synthesize evidence. Two devices are currently available in contemporary clinical practice: a dual 4 Fr-catheter, fluoroscopy-guided radiofrequency system (WavelinQ) and a single 6 Fr-catheter, ultrasound-guided thermal resistance system (Ellipsys). Across prospective studies and real-world series, endoAVF creation is consistently reported to have high technical success, with low major complication and infection rates. Clinical usability can often be achieved within weeks when ultrasound-based surveillance and protocol-driven maturation assistance are implemented; however, adjunctive procedures are frequently required and should be anticipated in program planning and informed consent. Observational comparisons and pooled analyses indicate broadly comparable functional outcomes versus surgery in selected cohorts, while estimates of primary patency and maintenance burden vary substantially across studies. Overall, endoAVFs represent a feasible, minimally invasive, vessel-sparing option that can be integrated into multidisciplinary access pathways in anatomically suitable candidates and experienced centers, complementing rather than replacing surgical strategies within a distal-first plan. Recent society practice guidance further emphasizes standardized mapping, expectation setting, troubleshooting algorithms for non-maturation, and dialysis-unit cannulation training to support consistent implementation. Pragmatic comparative studies and long-term registries using standardized endpoints, paired with healthcare-system-specific economic analyses, are needed to better define durability, resource use, and patient-centered outcomes over the full-access life cycle.

Indexed as

Ellipsysendovascular arteriovenous fistulahemodialysisnative arteriovenous fistulapercutaneous AVF creationvascular accessWavelinQ

Identifiers

PMID41827270
PMCPMC12985730

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.