Evidence map›Paper›PMID 41827182›Full record

ReviewJournal of clinical medicine2026

Pancreatic Cystic Lesions and Endoscopic Ultrasound Diagnostic Equipment: A Literature Review.

Marcantonio Gesualdo, Francesco Savino, Marco Pedote, Vito Affatato, Fabio Castellano, Andrea Iannone, Martino Mezzapesa, Antonella Contaldo, Giuseppe Losurdo, Mariabeatrice Principi

Abstract readReview
In one paragraph

Review in Journal of clinical medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Marcantonio GesualdoSection of Gastroenterology, Department of Precision and Regenerative Medicine and Jonian Area, University of Bari, 70124 Bari, Italy.ORCID 0000-0003-4446-1768
Francesco SavinoSection of Gastroenterology, Department of Precision and Regenerative Medicine and Jonian Area, University of Bari, 70124 Bari, Italy.
Marco PedoteSection of Gastroenterology, Department of Precision and Regenerative Medicine and Jonian Area, University of Bari, 70124 Bari, Italy.
Vito AffatatoSection of Gastroenterology, Department of Precision and Regenerative Medicine and Jonian Area, University of Bari, 70124 Bari, Italy.
Fabio CastellanoSection of Gastroenterology, Department of Precision and Regenerative Medicine and Jonian Area, University of Bari, 70124 Bari, Italy.
Andrea IannoneSection of Gastroenterology, Department of Precision and Regenerative Medicine and Jonian Area, University of Bari, 70124 Bari, Italy.
Martino MezzapesaSection of Gastroenterology, Department of Precision and Regenerative Medicine and Jonian Area, University of Bari, 70124 Bari, Italy.
Antonella ContaldoSection of Gastroenterology, Department of Precision and Regenerative Medicine and Jonian Area, University of Bari, 70124 Bari, Italy.
Giuseppe LosurdoSection of Gastroenterology, Department of Precision and Regenerative Medicine and Jonian Area, University of Bari, 70124 Bari, Italy.ORCID 0000-0001-7038-3287
Mariabeatrice PrincipiSection of Gastroenterology, Department of Precision and Regenerative Medicine and Jonian Area, University of Bari, 70124 Bari, Italy.ORCID 0000-0003-0545-5656

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pancreatic cystic lesions (PCLs) include clinically challenging conditions that range from benign to malignant prognoses. Their prevalence is increasing, and they are often detected as incidental findings during cross-sectional imaging. Thus, endoscopic ultrasound (EUS) plays a pivotal role in investigating these lesions. In this review, we analyze the complete diagnostic potential of EUS. Contrast-enhanced EUS, contrast-harmonic EUS, and elastography are useful for distinguishing between benign and malignant forms, and detective flow imaging EUS and e-FLOW EUS have enhanced the diagnostic arsenal available. Fine-needle aspiration (FNA) is important for obtaining cystic fluid for biochemical analysis and cytological examinations. Confocal laser endomicroscopy and through-the-needle biopsy represent adjunctive techniques for refined and difficult diagnosis. Moreover, artificial intelligence could be a promising modality in the EUS world. EUS allows PCLs to be detected accurately and plays a relevant role in identifying malignant forms.

Indexed as

confocal laser endomicroscopyendoscopic ultrasoundfine-needle aspirationpancreatic cystic lesionsthrough-the-needle biopsy

Identifiers

PMID41827182
PMCPMC12985895

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.