ArticleTropical diseases, travel medicine and vaccines2026
Impact of seasonal changes on the epidemiology of Lassa fever in a state in North Central, Nigeria.
Article in Tropical diseases, travel medicine and vaccines, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundLassa fever is a recurrent public health threat in Nigeria, particularly in endemic regions such as Kogi State. Its transmission is closely tied to environmental and seasonal dynamics, especially those influencing rodent populations. Understanding these climatic influences is essential for strengthening disease surveillance and implementing timely interventions.
methodsA descriptive cross-sectional study was conducted using retrospective epidemiological and climatic data from 2019 to 2024. Confirmed Lassa fever case records and meteorological variables (temperature, rainfall, and humidity) were analyzed using statistical correlation, regression models, and geospatial mapping.
resultsA consistent seasonal trend was observed, with the majority of cases occurring during the dry season (November–March), peaking in January 2022 and February 2024. Temperature showed a statistically significant positive correlation with Lassa fever incidence (r = 0.282, p = 0.029). Rainfall and humidity displayed weak or non-significant associations, though brief case surges followed isolated rainfall spikes in dry months. Spatial analysis identified Lokoja, Ibaji, and Dekina LGAs as hotspots, likely due to population density, food storage practices, and improved reporting. The regression model yielded modest explanatory power (R² = 0.089), but thresholds such as temperature > 35 °C and humidity between 60 and 80% emerged as potential early warning indicators.
conclusionSeasonal variation, particularly elevated temperatures during the dry season, plays a significant role in Lassa fever incidence in Kogi State. Integrating climatic, ecological, and epidemiological data into a real-time risk alert system under a One Health framework could enhance preparedness and response in high-risk areas. CLINICAL TRIALS NUMBER: Not applicable.
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