Evidence map›Paper›PMID 41826975›Full record

ArticleCost effectiveness and resource allocation : C/E2026

Cost-utility analysis of home mechanical ventilation compared to hospital settings in patients with chronic obstructive pulmonary disease.

Ondřej Gajdoš, Martin Rožánek, Gleb Donin, Vojtěch Kamenský

Abstract read
In one paragraph

Article in Cost effectiveness and resource allocation : C/E, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ondřej GajdošDepartment of Biomedical Technology, Faculty of Biomedical Engineering, Czech Technical University in Prague, nám. Sítná 3105, Kladno, 272 01, Czech Republic. ondrej.gajdos@fbmi.cvut.cz.
Martin RožánekDepartment of Biomedical Technology, Faculty of Biomedical Engineering, Czech Technical University in Prague, nám. Sítná 3105, Kladno, 272 01, Czech Republic.
Gleb DoninDepartment of Biomedical Technology, Faculty of Biomedical Engineering, Czech Technical University in Prague, nám. Sítná 3105, Kladno, 272 01, Czech Republic.
Vojtěch KamenskýDepartment of Biomedical Technology, Faculty of Biomedical Engineering, Czech Technical University in Prague, nám. Sítná 3105, Kladno, 272 01, Czech Republic.

Funding

Grant Agency of the Czech Technical University in Prague SGS24/153/OHK5/3T/17
6 · The paper itself

Abstract

backgroundChronic obstructive pulmonary disease is a chronic inflammatory disease that can be prevented and treated. The goals of therapy are to relieve symptoms, prevent disease progression, prevent exacerbations, improve general condition and physical performance, and reduce mortality. Mechanical ventilation is part of the standard treatment and can currently also be provided in the home environment. The aim of the study is to analyse the cost-effectiveness of home mechanical ventilation in adult patients with chronic obstructive pulmonary disease compared to facility-based mechanical ventilation from the perspective of a health care payer in the Czech Republic.

methodsA Markov model was used for the evaluation and its input parameters were obtained from the literature review and from the opinions of experts from home care and home mechanical ventilation companies. The cost-utility analysis was carried out over a time horizon of 10 years, including sensitivity analyses and multiple scenario analyses.

resultsThe cumulative costs per person of home mechanical ventilation are CZK 2,378,660 and the cumulative costs per person of the facility-based mechanical ventilation are CZK 5,793,883. The cumulative utilities per person of home mechanical ventilation are 1.20 QALY and the cumulative utilities per person of facility-based mechanical ventilation are 1.16 QALY. The incremental cost-utility ratio is -73,131,881 CZK/QALY. Sensitivity analyses and multiple scenario analyses showed no changes.

conclusionsHome mechanical ventilation was shown to be cost-effective for patients with chronic obstructive pulmonary disease, because it strongly dominates mechanical ventilation in a health care facility.

Indexed as

COPDCost-utility analysisMarkov modelMechanical ventilation

Identifiers

PMID41826975
PMCPMC13097547

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.