Evidence map›Paper›PMID 41826888›Full record

ArticleBMC musculoskeletal disorders2026

The predictive effect of Kellgren-Lawrence grade and joint space height on pain and functional outcome.

Anni Rajamäki, Lari Lehtovirta, Aleksi Reito, Mika Niemeläinen, Antti Eskelinen

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Article in BMC musculoskeletal disorders, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Anni RajamäkiCoxa Hospital for Joint Replacement, Niveltie 4, Tampere, 33520, Finland. anni.rajamaki@tuni.fi.ORCID http://orcid.org/0000-0001-8046-2747
Lari LehtovirtaCoxa Hospital for Joint Replacement, Niveltie 4, Tampere, 33520, Finland.ORCID http://orcid.org/0000-0002-9391-8915
Aleksi ReitoCoxa Hospital for Joint Replacement, Niveltie 4, Tampere, 33520, Finland.ORCID http://orcid.org/0000-0002-6903-6461
Mika NiemeläinenCoxa Hospital for Joint Replacement, Niveltie 4, Tampere, 33520, Finland.ORCID http://orcid.org/0000-0002-9438-111X
Antti EskelinenCoxa Hospital for Joint Replacement, Niveltie 4, Tampere, 33520, Finland.ORCID http://orcid.org/0000-0003-0302-0253

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPlain radiographs play a key role in the diagnosis of knee osteoarthritis (OA), with the Kellgren-Lawrence (KL) grading system being widely used to assess radiographic severity of the disease. Previous studies have suggested that radiographically less severe knee OA may be associated with inferior outcomes following total knee replacement (TKA). This study aimed to evaluate whether preoperative radiological findings are predictive of postoperative Oxford Knee Score (OKS) and residual knee pain after primary TKA.

methodsWe retrospectively included all patients who underwent TKA at our high-volume joint replacement center in 2018. The primary outcome was the OKS collected at one year postoperatively. The secondary outcome was patient-reported knee pain at one year. Preoperative plain radiographs were graded using the KL classification, and joint space height was measured. Additional covariates included age, gender, BMI, ASA score, and specific comorbidities. Multivariable analyses were performed, and model performance was assessed using R

resultsA total of 1,401 patients were included. Patients with less severe osteoarthritis had lower postoperative OKS compared to those with more advanced disease. Similarly, a greater joint space height was associated with smaller improvements in OKS following TKA. In multivariable models, the R

conclusionIn this large single-center cohort, comprehensive clinical and radiographic data were analyzed using advanced statistical methods. Our findings support previous evidence suggesting that comparatively less severe radiographic OA is associated with less favorable outcomes after TKA. However, the limited predictive capacity of the models highlights the multifactorial nature of postoperative outcomes and the challenges faced in forecasting patient-reported results following TKA.

Indexed as

ArthralgiaArthroplasty, Replacement, KneeKnee JointOsteoarthritis, KneePostoperative PainAgedFemaleHumansMaleMiddle AgedPain MeasurementPredictive Value of TestsRadiographyRecovery of FunctionRetrospective StudiesSeverity of Illness IndexKellgren-LawrenceOsteoarthritisOxford knee scorePostoperative painTKATotal knee arthroplasty

Identifiers

PMID41826888
PMCPMC13101260

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.