Severe intracranial infectious complication after sclerotherapy in facial venous malformations: a case report.

Zilu Wang, Qianyun Han, Mingzhe Wen, Deming Wang, Lixin Su, Yi Sun, Xindong Fan

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Article in International journal of emergency medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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7 authors.

Zilu WangDepartment of Interventional Therapy, Multidisciplinary Team of Vascular Anomalies, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University, Shanghai, 200011, PR China.

Qianyun HanDepartment of Interventional Therapy, Multidisciplinary Team of Vascular Anomalies, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University, Shanghai, 200011, PR China.

Mingzhe WenDepartment of Interventional Therapy, Multidisciplinary Team of Vascular Anomalies, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University, Shanghai, 200011, PR China.

Deming WangDepartment of Interventional Therapy, Multidisciplinary Team of Vascular Anomalies, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University, Shanghai, 200011, PR China.

Lixin SuDepartment of Interventional Therapy, Multidisciplinary Team of Vascular Anomalies, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University, Shanghai, 200011, PR China.

Yi Sun *Department of Interventional Therapy, Multidisciplinary Team of Vascular Anomalies, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University, Shanghai, 200011, PR China. sunyi219@163.com.ORCID http://orcid.org/0000-0002-6154-5341

Xindong Fan *Department of Interventional Therapy, Multidisciplinary Team of Vascular Anomalies, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University, Shanghai, 200011, PR China. fanxindong@aliyun.com.ORCID http://orcid.org/0000-0002-8117-4541

Funding

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6 · The paper itself

Abstract

backgroundVenous malformations are common slow-flow vascular malformations. Sclerotherapy shows satisfactory efficacy in venous malformations, with generally manageable complications. Post-procedural infection is rarely reported. CASE PRESENTATION: A 44-year-old male patient with extensive facial venous malformations developed severe infection in the left facial region and the central nervous system following a routine sclerotherapy. The patient’s condition rapidly worsened after admission, with repetitive convulsions of the mouth and limbs. Burr hole drainage was performed and antimicrobial and antiepileptic therapies were administered. The patient was discharged with his infection well-controlled, but reported epilepsy sequelae at 1-year follow-up.

conclusionThis case highlights that intracranial infection is a rare but severe complication of sclerotherapy in facial venous malformations. Early identification through timely neuroimaging and prompt anti-infective treatment are critical to the prognosis.

Indexed as

ComplicationInfectionSclerotherapySubdural empyemaVenous malformations

Identifiers

PMID41826807

DOI10.1186/s12245-026-01177-2

PMCPMC13101384

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