Evidence map›Paper›PMID 41826671›Full record

ArticleJournal of perinatology : official journal of the California Perinatal Association2026

Language and sound exposure across neonatal intensive care hospitalization and relationships with early outcome.

R Pineda, L J Woodward, Z A Vesoulis, C D Smyser, T E Inder, A M Mathur, B L Schlaggar

Abstract read
In one paragraph

Article in Journal of perinatology : official journal of the California Perinatal Association, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

R PinedaChan Division of Occupational Science and Occupational Therapy, University of Southern California, Los Angeles, CA, USA. bobbi.pineda@chan.usc.edu.ORCID http://orcid.org/0000-0001-9240-4798
L J WoodwardFaculty of Health, University of Canterbury, Christchurch, New Zealand.
Z A VesoulisDepartment of Neurology, Pediatrics, Radiology, Psychiatry, and Neurosurgery, Washington University, St. Louis, MO, USA.ORCID http://orcid.org/0000-0001-8290-0069
C D SmyserDepartment of Neurology, Pediatrics, Radiology, Psychiatry, and Neurosurgery, Washington University, St. Louis, MO, USA.ORCID http://orcid.org/0000-0002-4716-5190
T E InderCenter for Perinatal and Infant Research, Children's Hospital of Orange County, Department of Pediatrics, University of California, Irvine, CA, USA.
A M MathurDepartment of Neurology, Pediatrics, Radiology, Psychiatry, and Neurosurgery, Washington University, St. Louis, MO, USA.
B L SchlaggarKennedy Krieger Institute, Baltimore, MD, USA.

Funding

WU INSTITUTE OF CLINICAL AND TRANSLATIONAL SCIENCESUL1TR002345 · NCATS · WASHINGTON UNIVERSITY · PI William G. Powderly · 2017 to 2026
$97.8M
Washington University Institute of Clinical and Translational SciencesUL1TR000448 · NCATS · WASHINGTON UNIVERSITY · PI EVANOFF, BRADLEY A · 2012 to 2016
$41.4M
WUIDDRC Supplement-Supporting the health and well-being of children with intellectual and developmental disability during COVID-19 pandemicP50HD103525 · NICHD · WASHINGTON UNIVERSITY · PI JOSEPH D DOUGHERTY, Natasha Marrus · 2020 to 2026
$15.5M
MULTICENTER CAREER DEVELOPMENT PROGRAM FOR PHYSICAL AND OCCUPATIONAL THERAPYK12HD055931 · NICHD · WASHINGTON UNIVERSITY · PI HAYES, MARCIE HARRIS · 2007 to 2021
$12.7M
NCATS NIH HHS UL1 TR000448NCATS NIH HHS UL1 TR002345NICHD NIH HHS K12 HD055931NICHD NIH HHS P50 HD103525U.S. Department of Health & Human Services | NIH | Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) K12 HD055931U.S. Department of Health & Human Services | NIH | Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) P50 HD103525U.S. Department of Health & Human Services | NIH | National Center for Advancing Translational Sciences (NCATS) UL1 TR000448
6 · The paper itself

Abstract

objectivesExamine relationships between quantitative measures of language and sound exposure in the NICU and infant neurobehavior. STUDY

designSixty-four preterm infants (≤28 weeks of gestation) had language and sound exposure measured across four time points: within two weeks of birth and at 30, 34, and 35-41 weeks postmenstrual age (PMA). Neurobehavior was assessed at 35-41 weeks PMA using the NICU Network Neurobehavioral Scales.

resultsHigher average decibel levels in the NICU environment were associated with lower infant orientation scores (p = 0.04, β = -0.33). Higher peak decibel levels were associated with greater hypertonia (p = 0.01, β = 0.37). More electronic sound exposure was associated with less infant hypotonia (p = 0.047; β = -0.003). Increased silence was associated with greater infant hypertonia (p = 0.01; β = 0.001). Higher adult word counts were related to lower infant stress (p = 0.045, β = -1.37).

conclusionNICU sound exposures were related to neonatal neurobehavior near term age, highlighting the neurological impact of the auditory environment on preterm infants.

Indexed as

Infant BehaviorInfant, PrematureIntensive Care Units, NeonatalLanguageNoiseSoundFemaleGestational AgeHumansInfant, NewbornMaleMuscle HypertoniaMuscle Hypotonia

Identifiers

PMID41826671
PMCPMC13200613

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.