Evidence map›Paper›PMID 41826662›Full record

ArticleJournal of perinatology : official journal of the California Perinatal Association2026

Neurodevelopmental impairment in preterm infants following progressive post-hemorrhagic ventricular dilatation.

Grace M Musiime, Leonora Hendson, Khorshid Mohammad, Grace P S Kwong, Jay Riva-Cambrin, Amina Benlamri, Selphee Tang, James N Scott, Sarfaraz Momin, Hussein Zein and 1 more

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In one paragraph

Article in Journal of perinatology : official journal of the California Perinatal Association, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Grace M MusiimeDepartment of Pediatrics, Section of Newborn Critical Care, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada.ORCID http://orcid.org/0000-0001-5278-2284
Leonora HendsonDepartment of Pediatrics, Section of Newborn Critical Care, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada.
Khorshid MohammadDepartment of Pediatrics, Section of Newborn Critical Care, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada.
Grace P S KwongAlberta Children's Hospital Research Institute, University of Calgary, Calgary, AB, Canada.ORCID http://orcid.org/0000-0002-9081-6059
Jay Riva-CambrinAlberta Children's Hospital Research Institute, University of Calgary, Calgary, AB, Canada.
Amina BenlamriDepartment of Pediatrics, Section of Newborn Critical Care, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada.
Selphee TangDepartment of Pediatrics, Section of Newborn Critical Care, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada.
James N ScottDepartment of Radiology, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada.
Sarfaraz MominDepartment of Pediatrics, Section of Newborn Critical Care, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada.
Hussein ZeinDepartment of Pediatrics, Section of Newborn Critical Care, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada.
Lara M LeijserDepartment of Pediatrics, Section of Newborn Critical Care, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada. lara.leijser@ucalgary.ca.ORCID http://orcid.org/0000-0001-5458-3721

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo investigate the relationship of post-hemorrhagic ventricular dilatation (PHVD) with neurodevelopmental outcomes in preterm infants. STUDY

designRetrospective cohort study of infants <29 weeks' gestation admitted from 2010-2018 with intraventricular hemorrhage and neurodevelopmental assessment at 18-21 months corrected age. Eligible infants were grouped as 'no PHVD', 'PHVD without neurosurgical intervention', and 'symptomatic PHVD with intervention'. Neurodevelopmental impairment (NDI) was assessed using generalized linear models.

resultsOf 227 infants, 183 (80.6%) had no PHVD, 28 (12.3%) had PHVD without intervention, and 16 (7.0%) had PHVD with intervention. Severe NDI was observed in 14 (7.7%), 10 (35.7%), and 10 (62.5%) infants, respectively (p < 0.05). PHVD without and with intervention was associated with significantly increased risk of overall NDI (adjusted odds ratios [aOR] 6.2, 95% CI 2.4-16.5 and 18.1, 95% CI 5.5-68.4) as compared to no PHVD.

conclusionsProgressive PHVD, irrespective of clinical symptoms, predisposes affected preterm infants to significant risk of NDI.

Indexed as

Cerebral HemorrhageCerebral Intraventricular HemorrhageCerebral VentriclesInfant, Premature, DiseasesNeurodevelopmental DisordersDilatation, PathologicFemaleGestational AgeHumansInfantInfant, NewbornInfant, PrematureMaleRetrospective Studies

Identifiers

PMID41826662

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.