The impact of body mass index on treatment response to high-dose dexamethasone in adult primary immune thrombocytopenia patients: A two-center retrospective study.

Abdulkerim Yıldız, Rafiye Çiftçiler, Samet Yaman, Minura Abishova Aliyeva, Sedat Acar, Shabnam Shahab, Huriye Baysal

Abstract readMulticenter Study

In one paragraph

Article in Internal and emergency medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Abdulkerim YıldızDepartment of Hematology, Faculty of Medicine, Erol Olçok Training and Research Hospital, Hitit University, Çorum, Turkey. akerim@hotmail.com.ORCID http://orcid.org/0000-0002-9596-4042

Rafiye ÇiftçilerDivision of Hematology, Department of Internal Medicine, Faculty of Medicine, Selçuk University, Konya, Turkey.

Samet YamanDepartment of Hematology, Faculty of Medicine, Erol Olçok Training and Research Hospital, Hitit University, Çorum, Turkey.

Minura Abishova AliyevaDepartment of Hematology, Melhem International Hospital, Baku, Azerbaijan.

Sedat AcarDepartment of Internal Medicine, Faculty of Medicine, Erol Olçok Training and Research Hospital, Hitit University, Çorum, Turkey.

Shabnam ShahabDepartment of Internal Medicine, Faculty of Medicine, Selçuk University, Konya, Türkiye.

Huriye BaysalDepartment of Internal Medicine, Faculty of Medicine, Selçuk University, Konya, Türkiye.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

High-dose dexamethasone (HDD) is widely used as first-line therapy for immune thrombocytopenia (ITP) and is administered at a fixed dose regardless of body weight. The impact of body mass index (BMI) on treatment response to HDD remains unclear. This retrospective, two-center study included 60 adult patients with newly diagnosed ITP who received HDD as first-line therapy. Demographic characteristics, BMI, baseline laboratory values, and treatment responses at 1, 6, and 12 months were analyzed. BMI was evaluated using cut-off values of 25, 27, and 30. The median number of HDD cycles administered was 1 (range: 1-4), and the median BMI at diagnosis was 27.0 kg/m

Indexed as

Body Mass IndexDexamethasonePurpura, Thrombocytopenic, IdiopathicAdultAgedFemaleHumansMaleMiddle AgedRetrospective StudiesTreatment OutcomeDexamethasoneBody mass indexDexamethasoneImmune thrombocytopeniaResponse

Identifiers

PMID41826572

DOI10.1007/s11739-026-04318-w

PMCPMC13263306

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.