Evidence map›Paper›PMID 41826416›Full record

ArticleScientific reports2026

Skin-to-skin contact significantly impacts maternal anxiety, mother-infant bonding, and autonomic function in infants with congenital heart disease and their mothers.

Alexa Asch, Rathinaswamy B Govindan, Ellen Bartolini, Venkata Chaitanya Chirumamilla, Cara Pleau, Mandana O'Donnell, Sarah D Schlatterer

Abstract read
In one paragraph

Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Effects of Maternal Heartbeat Exposure on Neonatal Autonomic Regulation.Pathophysiology : the official journal of the International Society for Pathophysiology · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Alexa AschZickler Family Prenatal Pediatrics Institute, Children's National Hospital, Washington, DC, USA.
Rathinaswamy B GovindanZickler Family Prenatal Pediatrics Institute, Children's National Hospital, Washington, DC, USA.
Ellen BartoliniZickler Family Prenatal Pediatrics Institute, Children's National Hospital, Washington, DC, USA.
Venkata Chaitanya ChirumamillaZickler Family Prenatal Pediatrics Institute, Children's National Hospital, Washington, DC, USA.
Cara PleauDivision of Cardiology, Children's National Hospital, Washington, DC, USA.
Mandana O'DonnellDivision of Physical Medicine and Rehabilitation, Children's National Hospital, Washington, DC, USA.
Sarah D SchlattererZickler Family Prenatal Pediatrics Institute, Children's National Hospital, Washington, DC, USA. sschlatt@childrensnational.org.ORCID http://orcid.org/0000-0002-6735-5776

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mothers of infants in the cardiac intensive care unit (CICU) experience stress, anxiety, and impaired bonding. Infants with congenital heart disease (CHD) experience dysregulation of autonomic function. Skin-to-skin contact (SSC) alleviates stress in both mothers and infants, but its use remains understudied in the CHD population. In this single-center, prospective pilot study, we evaluated the impact of low-dose postoperative SSC (three sessions within a 10-day period) on maternal mood, measured by the State Trait Anxiety Inventory (STAI-6) and the Depression Anxiety Stress Scale (DASS-21), mother-infant bonding, and autonomic function, measured by heart rate variability (HRV), in infants with CHD and their mothers. Twenty-one mother-infant dyads participated in 51 SSC sessions. STAI-6 and bonding scores significantly improved after just one session of SSC (p < 0.001, p = 0.004, respectively). All metrics of HRV-low frequency (LF) (p < 0.001), high frequency (HF) (p < 0.001), the standard deviation of normal-to-normal intervals (SDNN) (p < 0.001), the root mean square of successive differences RMSSD (p = 0.032), and the SDNN/ RMSSD ratio (p < 0.001)-significantly decreased during SSC in mothers. LF (p = 0.036), HF (p = 0.034), and the SDNN/ RMSSD ratio (p = 0.008) significantly decreased during SSC in infants. Our data suggest that low-dose SSC significantly impacts autonomic function of both mothers and CHD infants and improves maternal anxiety and perceptions of bonding, although more studies are needed to understand the relationship between HRV and stress in this population.

Indexed as

AnxietyAutonomic Nervous SystemHeart Defects, CongenitalKangaroo-Mother Care MethodMother-Child RelationsMothersObject AttachmentAdultFemaleHeart RateHumansInfantMalePilot ProjectsProspective StudiesStress, PsychologicalAutonomic Nervous SystemCongenital Heart DiseaseHeart Rate VariabilityMaternal StressMother-Infant BondingSkin-to-Skin Contact

Identifiers

PMID41826416
PMCPMC13106637

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.