Evidence map›Paper›PMID 41825932›Full record

ArticleBMJ paediatrics open2026

Longitudinal effects of the COVID-19 pandemic on infant and toddler development: a retrospective cohort study.

Gretchen Domek, Harisa Spahic, Alyssa Cole, Lori Silveira, Tyler Igoe, Amy Reyes, Brandi Freeman

Abstract read
In one paragraph

Article in BMJ paediatrics open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Gretchen DomekDepartment of Pediatrics, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA gretchen.domek@childrenscolorado.org.ORCID http://orcid.org/0000-0002-3391-5114
Harisa SpahicDepartment of Pediatrics, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA.
Alyssa ColeUniversity of Colorado School of Medicine, Aurora, Colorado, USA.
Lori SilveiraDepartment of Pediatrics, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA.
Tyler IgoeUniversity of Colorado School of Medicine, Aurora, Colorado, USA.
Amy ReyesUniversity of Colorado School of Medicine, Aurora, Colorado, USA.
Brandi FreemanDepartment of Pediatrics, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo determine if developmental outcomes differed at 24 months between US children born before and during the pandemic.

designThis retrospective cohort study included children completing a 24-month well visit between 1 March 2019 and 31 December 2022. MAIN OUTCOMES/MEASURES: Main outcomes included 24-month Ages & Stages Questionnaire (ASQ-3) domain scores, total score and percentage of children classified as atypical (≥1 SD below the domain mean). Multivariable regression adjusted for child age, sex and insurance. For the transitional cohort, regression models assessed relationships between ASQ-3 measures and duration of pandemic exposure.

resultsOf 604 children, most were Hispanic/Latino (37%) or Black (26%) and on government-sponsored insurance (77%). Compared with prepandemic, pandemic children scored lower for total ASQ-3 (250 vs 262, p=0.03), communication (45 vs 49, p=0.02) and personal-social (49 vs 52, p=0.03) and had higher odds of atypical scores for fine motor (2.2, 95% CI 1.2 to 4.2; p=0.01), with males more likely to have atypical scores for communication (2.2, 95% CI 1.2 to 4.0; p=0.03) and fine motor (2.3, 95% CI 1.0 to 5.0; p=0.04). For the transitional cohort, pandemic exposure was negatively associated with total ASQ-3 (p=0.048), communication (p=0.02) and personal-social (p=0.03).

conclusionsFindings suggest a negative association of the COVID-19 pandemic with early child development, especially for emerging language and socioemotional skills, with males likely affected more than females.

Indexed as

Child DevelopmentCOVID-19Child, PreschoolFemaleHumansInfantMalePandemicsRetrospective StudiesSARS-CoV-2United StatesChild HealthCOVID-19Infant

Identifiers

PMID41825932
PMCPMC12993314

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.