Evidence map›Paper›PMID 41825471›Full record

ArticleThe Lancet. Planetary health2026

Heat waves and annual mortality among older adults (aged ≥65 years) in the USA.

James P Healy, Edgar Castro, Mahdieh Danesh Yazdi, Mary B Rice, Howard Chang, Kyle Steenland, Yaguang Wei, Joel D Schwartz

Abstract read
In one paragraph

Article in The Lancet. Planetary health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Extreme Heat and Emergency Health Impacts in the US (2018-2025).International journal of environmental research and public health · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

James P HealyDepartment of Environmental Health, Department of Epidemiology, Harvard T H Chan School of Public Health, Boston, MA, USA.
Edgar CastroDepartment of Environmental Health, Department of Epidemiology, Harvard T H Chan School of Public Health, Boston, MA, USA.
Mahdieh Danesh YazdiDepartment of Environmental Health, Department of Epidemiology, Harvard T H Chan School of Public Health, Boston, MA, USA; Program in Public Health, Department of Family, Population, and Preventive Medicine, Stony Brook University School of Medicine, Stony Brook, NY, USA.
Mary B RiceDepartment of Environmental Health, Department of Epidemiology, Harvard T H Chan School of Public Health, Boston, MA, USA; Division of Pulmonary, Critical Care and Sleep Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.
Howard ChangGangarosa Department of Environmental Health, Emory Rollins School of Public Health, Atlanta, GA, USA.
Kyle SteenlandGangarosa Department of Environmental Health, Emory Rollins School of Public Health, Atlanta, GA, USA.
Yaguang WeiDepartment of Environmental Health, Department of Epidemiology, Harvard T H Chan School of Public Health, Boston, MA, USA; Department of Environmental Medicine and Climate Science, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Joel D SchwartzDepartment of Environmental Health, Department of Epidemiology, Harvard T H Chan School of Public Health, Boston, MA, USA; Department of Epidemiology, Harvard T H Chan School of Public Health, Boston, MA, USA. Electronic address: jschwrtz@hsph.harvard.edu.

Funding

Identifying low dose measurement error corrected effects of multiple pollutants using causal modelingR01ES032418 · NIEHS · HARVARD UNIVERSITY D/B/A HARVARD SCHOOL OF PUBLIC HEALTH · PI SCHWARTZ, JOEL D · 2021 to 2024
$1.7M
Individual& community factors conveying vulnerability to weather extremesR21ES020695 · NIEHS · HARVARD SCHOOL OF PUBLIC HEALTH · PI SCHWARTZ, JOEL D · 2011 to 2012
$445k
NIEHS NIH HHS R01 ES032418NIEHS NIH HHS R21 ES020695
6 · The paper itself

Abstract

backgroundHeat waves are increasing in frequency and intensity due to climate change. While acute mortality effects are well documented, the impact on annual mortality and the modification of this association by race, poverty level, and amount of green space at a national level are less understood. We aimed to quantify the association of heat waves with annual all-cause and cause-specific mortality among older adults in the contiguous USA.

methodsWe conducted a cohort study using an open cohort of 73 769 163 Medicare beneficiaries (aged ≥65 years) residing in 27 926 ZIP codes across the contiguous USA from 2000-18, with 668 448 618 person-years of follow-up. Heat waves were defined at the ZIP-code level as 2 or more consecutive days with a minimum temperature exceeding 2·5 SDs above the local 30-year summer mean. We used quasi-Poisson regression models at the ZIP-code-year level to examine the association between the annual number of heat waves and mortality counts, adjusting for individual and neighbourhood-level characteristics and secular trends.

findingsAn additional heat wave was associated with an increase in the annual mortality rate of 8·83 deaths per 10 000 person-years (95% CI 5·99 to 11·68). Across the contiguous USA from 2000-18, the 8307 observed heat waves were associated with an estimated 17 603 (95% CI 11 942 to 23 287) excess deaths. Were an additional heat wave to occur in every ZIP code each decade, we estimated 56 815 (95% CI 38 651 to 74 979) premature deaths would result. Increased heatwaves were associated with cardiovascular, respiratory, and neurological deaths. In subgroup analyses, the mortality increase was significantly greater for Black individuals (16·50 per 10 000 person-years, 95% CI 8·11 to 25·04) than for White individuals (5·85 per 10 000 person-years, 2·79 to 8·93). The association was stronger in high-poverty neighbourhoods (11·09, 4·00 to 18·29) and was protective in neighbourhoods with abundant green space (-13·51, -24·92 to -1·79).

interpretationHeat waves are associated with a substantial increase in annual mortality among older US adults, with disproportionate impacts on Black communities and communities on low incomes. Our findings suggest that climate change poses a significant chronic risk to public health, highlighting the need for urgent mitigation and targeted adaptation measures to address these inequities.

fundingNone.

Indexed as

Hot TemperatureMortalityAgedAged, 80 and overClimate ChangeCohort StudiesFemaleHumansMaleUnited States

Identifiers

PMID41825471
PMCPMC13024048

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.