Evidence map›Paper›PMID 41825364›Full record

ArticleUltrasonics sonochemistry2026

Ultrasound-modified soy protein-hyaluronic acid conjugates for swallowing-friendly high internal phase pickering emulsion gels: structure, properties, and applications.

Yang Wang, Zhanqiang Ma, Yueru Liu, Yuetong Gong

Abstract read
In one paragraph

Article in Ultrasonics sonochemistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yang WangSchool of Food Engineering, Harbin University, Harbin 150086, China. Electronic address: yangyang4677532@163.com.
Zhanqiang MaCollege of Food Science, Northeast Agricultural University, Harbin 150030, China.
Yueru LiuCollege of Food Science, Northeast Agricultural University, Harbin 150030, China.
Yuetong GongCollege of Food Science, Northeast Agricultural University, Harbin 150030, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

With the increasing global aging population, there is a growing demand for safe and nutritious specialized foods tailored to individuals with dysphagia. However, designing foods with suitable texture, stability, and swallowability remains a significant challenge. This study explores the use of high-intensity ultrasound (HIU)-modified soy protein isolate (SPI)/hyaluronic acid (HA) complexes and conjugates to fabricate high internal phase Pickering emulsion gels (HIPPEGs) suitable for dysphagia patients. The formation of the SPI/HA conjugate was demonstrated by SDS-PAGE and degree of grafting. Compared to SPI alone, the HIU-treated conjugate exhibited smaller particle size, higher surface charge, greater surface hydrophobicity, and enhanced structural flexibility, leading to superior emulsifying performance. Rheological analysis confirmed that HIPPEGs stabilized by U-Conjugate possessed higher gel strength. Texture profile and IDDSI tests indicated a soft texture, low adhesiveness, and favorable swallowability-all meeting the requirements for dysphagia diets. LF-NMR and CLSM analyses further revealed uniform water distribution and a dense, homogeneous microstructure. Moreover, U-Conjugate-stabilized HIPPEGs demonstrated potential for in vitro quercetin delivery and suitability for 3D printing applications. In conclusion, this study provides an effective strategy for developing high-performance HIPPEGs with strong potential for application in dysphagia-friendly food design, particularly highlighting their capabilities in nutrient delivery and 3D printing.

Indexed as

DeglutitionHyaluronic AcidSoybean ProteinsUltrasonic WavesEmulsionsGelsHydrophobic and Hydrophilic InteractionsEmulsionsGelsHyaluronic AcidSoybean ProteinsConjugateDysphagiaHIPPEGsHyaluronic acidSoy protein

Identifiers

PMID41825364
PMCPMC12990364

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.