Evidence map›Paper›PMID 41824916›Full record

SynthesisJornal brasileiro de nefrologia

Moraxella peritoneal dialysis-related infections: a systematic review.

John Dotis, Charalampos Antachopoulos, Vasiliki Karava, Athina Papadopoulou, Nikoleta Printza

Abstract readSystematic Review
In one paragraph

Synthesis in Jornal brasileiro de nefrologia. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

John DotisAristotle University of Thessaloniki, Hippokration Hospital, Third Department of Pediatrics, Thessaloniki, Greece.ORCID http://orcid.org/0000-0001-5217-1766
Charalampos AntachopoulosAristotle University of Thessaloniki, Hippokration Hospital, Third Department of Pediatrics, Thessaloniki, Greece.ORCID http://orcid.org/0000-0003-1416-8878
Vasiliki KaravaAristotle University of Thessaloniki, Hippokration Hospital, First Department of Pediatrics, Thessaloniki, Greece.ORCID http://orcid.org/0000-0003-3638-5179
Athina PapadopoulouNational and Kapodistrian University of Athens, Agia Sofia Children's Hospital, First Department of Pediatrics, Athens, Greece.ORCID http://orcid.org/0000-0003-4790-9521
Nikoleta PrintzaNational and Kapodistrian University of Athens, Agia Sofia Children's Hospital, First Department of Pediatrics, Athens, Greece.ORCID http://orcid.org/0000-0003-1618-9285

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionMoraxella species, although infrequent in peritoneal dialysis (PD)-associated infections, are established pathogens. Moraxella catarrhalis is recognized as a cause of upper and lower respiratory tract infections and is increasingly associated with β-lactamase production. The role of Moraxella species in PD-related infections warrants further investigation.

methodsA comprehensive search of PubMed and Google Scholar was conducted for cases of PD-associated infections caused by Moraxella. Inclusion criteria required a diagnosis of peritonitis or exit-site infection confirmed by culture. Demographic data, clinical presentation, microbiological identification, antimicrobial resistance, therapeutic regimens, and outcomes were analyzed.

resultsFourteen cases of Moraxella-related peritonitis in PD patients were identified between 1987 and 2024 from 13 studies, with no reports of exitsite infections. The mean age was 56 years; diabetic nephropathy was the most common underlying condition (four cases). M. catarrhalis (n = 6) and Moraxella osloensis (n = 5) were the most frequent pathogens. The most commonly reported methods were bacterial growth in culture media, followed by species identification using biochemical profiling or automated systems (n = 10), and advanced confirmatory techniques. Clinical presentation included abdominal pain, fever, and clouding of the dialysis fluid. Most isolates were susceptible to cephalosporins, aminoglycosides, and fluoroquinolones. The majority of patients (86%) retained their catheters after appropriate treatment, usually with intraperitoneal cephalosporins, achieving complete symptom resolution within a few days. Overall prognosis was favorable, with no mortality.

conclusionMoraxella species, although rare, should be considered in the differential diagnosis of PD-associated infections. Identification using advanced techniques allows effective treatment and favorable outcomes, often without the need for catheter removal.

Indexed as

MoraxellaMoraxellaceae InfectionsPeritoneal DialysisPeritonitisAnti-Bacterial AgentsHumansAnti-Bacterial Agents

Identifiers

PMID41824916
PMCPMC12987636

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.