Evidence map›Paper›PMID 41824814›Full record

ArticleMedicine2026

Distribution characteristics and clinical correlation of inhalant allergen sensitization in children with respiratory and allergic diseases.

Wei Wang, Qingling Liu, Qianqian Zhang, Dongqing Ma, Hong Wang

Abstract read
In one paragraph

Article in Medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Wei WangDepartment of Pediatrics, Civil aviation General Hospital, Beijing City, China.
Qingling Liu
Qianqian Zhang
Dongqing Ma

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This retrospective study investigated the distribution characteristics and clinical relevance of inhalant allergen sensitization in children with respiratory allergic diseases. Pediatric patients aged 3 to 14 years diagnosed with allergic rhinitis or asthma between January 2022 and December 2024 were included. Demographic variables, serum total immunoglobulin E (tIgE) levels, and specific immunoglobulin E (sIgE) sensitization to fifteen major inhalant allergens were analyzed. Sensitization patterns were compared across age groups, sex, and diagnostic subtypes, and correlations between tIgE and allergen sensitization burden were evaluated. A total of 107 children were included (51 with allergic rhinitis and 56 with asthma). House dust mite was the most prevalent inhalant allergen. Age was associated with sensitization to dog dander and mixed tree pollens, while sex differences were limited. No statistically significant differences in individual allergen sensitization were observed between allergic rhinitis and asthma after correction for multiple comparisons. Total IgE levels correlated positively with the number of sensitized allergens and were significantly associated with sensitization to major indoor allergens. These findings highlight the predominance of perennial indoor allergens and indicate that sensitization burden rather than disease subtype contributes more substantially to systemic IgE activation in pediatric respiratory allergic diseases.

Indexed as

AllergensAsthmaImmunoglobulin ERhinitis, AllergicAdolescentAnimalsChildChild, PreschoolFemaleHumansMaleRetrospective StudiesAllergensImmunoglobulin Eallergic rhinitisasthmainhalant allergenpediatric respiratory allergic diseasesspecific immunoglobulin Etotal immunoglobulin E

Identifiers

PMID41824814
PMCPMC12991711

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.