Evidence map›Paper›PMID 41824643›Full record

ArticleJournal of vascular research2026

Rapid Quantitative Imaging of Heterogeneous Tissue Hemoglobin Dynamics Using Spatial Frequency Domain Imaging.

Gordon T Kennedy, Rebecca Rowland, Amaan Mazhar, David J Cuccia, Anthony J Durkin

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of vascular research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Gordon T KennedyBeckman Laser Institute and Medical Clinic, University of California Irvine, Irvine, California, USA, gordon.kennedy@uci.edu.
Rebecca RowlandBeckman Laser Institute and Medical Clinic, University of California Irvine, Irvine, California, USA.
Amaan MazharModulim, Irvine, California, USA.
David J CucciaModulim, Irvine, California, USA.
Anthony J DurkinBeckman Laser Institute and Medical Clinic, University of California Irvine, Irvine, California, USA.

Funding

Spatial Frequency Domain Imaging for Burn Wound Severity AssessmentR01GM108634 · NIGMS · UNIVERSITY OF CALIFORNIA-IRVINE · PI DURKIN, ANTHONY J · 2014 to 2023
$2.8M
The Development of a Low-Cost, Quantitative Skin Imaging CameraR44AG055320 · NIA · MODULATED IMAGING, INC. · PI CUCCIA, DAVID J, MAZHAR, AMAAN · 2017 to 2018
$1.5M
NIA NIH HHS R44 AG055320NIGMS NIH HHS R01 GM108634
6 · The paper itself

Abstract

<p>Introduction: Arterial insufficiency is a key factor in chronic wounds, diabetes, and peripheral arterial disease, all of which impair vascular function. Accurate monitoring of tissue-level oxygenation and hemodynamics is critical for assessing outcomes in cases of vascular compromise. However, many existing tools only measure small, localized regions of tissue. This study evaluates spatial variation in oxygenation during a vascular occlusion test (VOT) using wide-field spatial frequency domain imaging (SFDI).

methodsTissue oxygenation and perfusion dynamics were assessed using SFDI to map oxygen saturation (StO

resultsStO

conclusionSpatial variation is critical when comparing tissue hemodynamics across time and subjects. Noncontact wide-field imaging enables assessment of heterogeneous tissue regions that are difficult to evaluate with probe-based methods. </p>.

Indexed as

HemoglobinsOxygenOxygen SaturationAdultBiomarkersFemaleHemodynamicsHumansMaleMicrocirculationMiddle AgedPredictive Value of TestsRegional Blood FlowTime FactorsBiomarkersHemoglobinsOxygenArterial insufficiencyMultispectral imagingQuantitative hemodynamicsSpatial frequency domain imagingTissue oximetry

Identifiers

PMID41824643
PMCPMC13245941

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.