Evidence map›Paper›PMID 41824404›Full record

Trial reportPloS one2026

Non-immersive virtual reality telerehabilitation for motor accuracy and precision in individuals with Cerebral Palsy: A non-randomized clinical trial.

Paula Lumy da Silva, Elisa de Jesus Valenzuela, Mariana Giovanelli de Carvalho, Anne Michelli Gomes Gonçalves Fontes, Juliana Perez Weingartner, Talita Dias da Silva-Magalhães, Íbis Ariana Peña de Moraes, Helen Dawes, Eduardo Dati Dias, Carlos Bandeira de Mello Monteiro

Abstract readClinical Trial
In one paragraph

Trial report in PloS one, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Paula Lumy da SilvaDepartment of Physiotherapy, Fundação Hermínio Ometto (FHO), São Paulo, Brazil.
Elisa de Jesus ValenzuelaPostgraduate Program in Rehabilitation Sciences, School of Medicine, University of São Paulo (USP), São Paulo, Brazil.
Mariana Giovanelli de CarvalhoResearch Group and Technological Applications in Rehabilitation of the School of Arts, Sciences and Humanities of the University of São Paulo (PATER EACH-USP), São Paulo, Brazil.
Anne Michelli Gomes Gonçalves FontesPostgraduate Program in Rehabilitation Sciences, School of Medicine, University of São Paulo (USP), São Paulo, Brazil.
Juliana Perez WeingartnerResearch Group and Technological Applications in Rehabilitation of the School of Arts, Sciences and Humanities of the University of São Paulo (PATER EACH-USP), São Paulo, Brazil.
Talita Dias da Silva-MagalhãesPostgraduate Program in Rehabilitation Sciences, School of Medicine, University of São Paulo (USP), São Paulo, Brazil.ORCID https://orcid.org/0000-0002-4683-4671
Íbis Ariana Peña de MoraesPostgraduate Program in Rehabilitation Sciences, School of Medicine, University of São Paulo (USP), São Paulo, Brazil.ORCID https://orcid.org/0000-0002-1672-2628
Helen DawesNational Institute for Health and Care Research, Exeter Biomedical Research Centre and HealthTech Research Centre, College of Medicine and Health, University of Exeter, Exeter, United Kingdom.ORCID https://orcid.org/0000-0002-2933-5213
Eduardo Dati DiasPostgraduate Program in Rehabilitation Sciences, School of Medicine, University of São Paulo (USP), São Paulo, Brazil.ORCID https://orcid.org/0000-0002-6649-3237
Carlos Bandeira de Mello MonteiroPostgraduate Program in Rehabilitation Sciences, School of Medicine, University of São Paulo (USP), São Paulo, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aimed to describe motor performance, accuracy and precision, in individuals with Cerebral Palsy (CP) compared to typically developing individuals (controls), and to examine longitudinal changes during a non-immersive virtual reality (VR) telerehabilitation protocol.

methodsThe final sample included, 38 with CP and 21 controls. Controls completed a single practice session, while 29 participants with CP completed the 10-day home-based protocol, and 20 returned for a follow-up session to assess retention. Analyses followed the intention-to-treat principle, including all 38 CP participants. The intervention used the MoveHero game, performed two to three times per week, with sessions lasting at least 9 minutes under remote therapist supervision. Motor performance was assessed in a coincident timing task using absolute error (AE, accuracy), variable error (VE, precision), and percentage of hits. The study was registered in the Brazilian Clinical Trials Registry (ReBec: RBR-4kf52bv).

resultsThe CP group had higher mean AE and VE values than controls but showed progressive improvements across practice days. Mean accuracy improved across most target positions (p < 0.05), with mean AE decreasing from 1350 ms on Day 1-895 ms on the best practice day. Controls had a mean AE of 584 ms, and participants with CP achieved similar performance in two of the four target positions. Mean VE improved notably for Target 3 (1124 ms on Day 1-811 ms on Day 9, p = 0.007), and the mean percentage of correct responses increased from 45.8% to 58.5% (p = 0.019), while controls reached 69.1%. No significant differences were found among GMFCS subgroups. Gains were maintained at follow-up (p > 0.05).

conclusionHome-based non-immersive VR telerehabilitation using MoveHero effectively enhanced upper-limb motor performance in individuals with CP, regardless of functional level. These findings support VR as an accessible, motivating, and adaptable tool for promoting motor learning and continuity of care in home-based rehabilitation.

Indexed as

Cerebral PalsyVirtual RealityAdolescentAdultChildFemaleHumansMaleMotor SkillsTelerehabilitationYoung Adult

Identifiers

PMID41824404
PMCPMC12987460

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.