Evidence map›Paper›PMID 41824059›Full record

ArticleOsteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA2026

Authors' reply to comment on: Effect of protein supplementation on hip bone mineral density, cortical thickness, and bone strength in older adult participants during a caloric restriction and aerobic exercise weight loss intervention: a randomized controlled trial.

Joshua Stapleton, Katelyn A Greene, Xiaoyan Leng, Leon Lenchik, Mary F Lyles, Barbara J Nicklas, Alexander M Baker, Benedikt Helgason, Karan Devane, Sue A Shapses and 2 more

Abstract readLetter
PubMed Full text at PMC Publisher
In one paragraph

Article in Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Joshua StapletonDepartment of Biomedical Engineering, Wake Forest University School of Medicine, Winston-Salem, NC, 27157, USA.
Katelyn A GreeneDepartment of Biomedical Engineering, Wake Forest University School of Medicine, Winston-Salem, NC, 27157, USA.
Xiaoyan LengDepartment of Biostatistics and Data Science, Wake Forest University School of Medicine, Winston-Salem, NC, 27157, USA.
Leon LenchikDivision of Radiologic Sciences, Wake Forest University School of Medicine, Winston-Salem, NC, 27157, USA.
Mary F LylesSection on Gerontology and Geriatric Medicine, Department of Internal Medicine, Wake Forest University School of Medicine, Winston-Salem, NC, 27157, USA.
Barbara J NicklasSection on Gerontology and Geriatric Medicine, Department of Internal Medicine, Wake Forest University School of Medicine, Winston-Salem, NC, 27157, USA.
Alexander M BakerThe Institute for Biomechanics, ETH Zurich, Zurich, Switzerland.
Benedikt HelgasonThe Institute for Biomechanics, ETH Zurich, Zurich, Switzerland.
Karan DevaneDepartment of Biomedical Engineering, Wake Forest University School of Medicine, Winston-Salem, NC, 27157, USA.
Sue A ShapsesDepartment of Nutritional Sciences, Rutgers University, New Brunswick, NJ, 08901, USA.
Denise K HoustonSection on Gerontology and Geriatric Medicine, Department of Internal Medicine, Wake Forest University School of Medicine, Winston-Salem, NC, 27157, USA.
Ashley A WeaverDepartment of Biomedical Engineering, Wake Forest University School of Medicine, Winston-Salem, NC, 27157, USA. ashley.weaver@wfusm.edu.ORCID http://orcid.org/0000-0002-4383-0106

Funding

Wake Forest Claude D. Pepper OAIC - RenewalP30AG021332 · NIA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI DALANE W KITZMAN · 2002 to 2026
$36.4M
Wake Forest Clinical and Translational Science AwardUL1TR001420 · NCATS · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI ARD, JAMY D, FOLEY, KRISTIE L · 2015 to 2023
$32.3M
Long-Term Effects of Weight Loss and Supplemental Protein on Physical FunctionR01AG050656 · NIA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI HOUSTON, DENISE KATHRYN · 2016 to 2020
$3.0M
Effect of protein supplementation during weight loss on older adult bone healthK25AG058804 · NIA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI WEAVER, ASHLEY · 2019 to 2023
$672k
Developing an Automated Image Analysis and Finite Element Modeling Platform to Assess the Effects of Supplemental Protein and Weight Loss on Bone Health in Obese Older AdultsF31AG069414 · NIA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI GREENE, KATELYN ANNE · 2020 to 2022
$138k
NCATS NIH HHS UL1 TR001420NIA NIH HHS F31 AG069414NIA NIH HHS K25 AG058804NIA NIH HHS P30 AG021332NIA NIH HHS R01 AG050656Swiss Federal Institute of Technology in Zurich Domain 2018-325
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID41824059
PMCPMC13403787

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.