ArticleClinical neuroradiology2026
Association Between Occluded Vessel Diameter and Clinical Outcomes of Mechanical Thrombectomy for M2 Occlusion.
Article in Clinical neuroradiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundThe association between occluded vessel diameter measured using pre-recanalization digital subtraction angiograms and clinical outcomes in patients with acute ischemic stroke undergoing mechanical thrombectomy for M2 occlusion remains unclear.
methodsConsecutive patients with acute ischemic stroke undergoing mechanical thrombectomy for M2 occlusion at our institution between January 2020 and December 2024 were retrospectively analyzed. Based on pre-recanalization digital subtraction angiograms, patients were classified as having large M2 occlusion (LM2O, ≥ 1.7 mm) or small M2 occlusion (SM2O, < 1.7 mm). Favorable 90-day outcome, defined as modified Rankin Scale 0-2 or recovery to pre-stroke level, were compared between the two groups.
resultsThere were 56 (58.3%) LM2O patients and 40 (41.7%) SM2O patients. Median occluded vessel diameter was 1.85 mm (IQR 1.78-2.11) for LM2O and 1.52 mm (IQR 1.43-1.62) for SM2O. LM2O patients were more likely to have dominant M2 occlusion (67.9% vs. 40.0%, P = 0.012), favorable outcome (62.5% vs. 25.0%; OR 6.67, 95% CI 2.59-17.15; P < 0.001), and first-pass effect (48.2% vs. 17.5%; OR 4.39, 95% CI 1.66-11.57; P = 0.002). In multivariable analysis, occluded vessel diameter ≥ 1.7 mm was independently associated with favorable outcome (OR 10.50, 95% CI 3.17-35.0; P < 0.001). Patients with a catheter-to-vessel ratio < 1.0 experienced higher first-pass effect more frequently than those with a catheter-to-vessel ratio ≥ 1.0 (46.8% vs. 24.5%; P = 0.032).
conclusionsOccluded M2 vessel diameter ≥ 1.7 mm may be associated with favorable 90-day outcome in patients with acute ischemic stroke undergoing mechanical thrombectomy for M2 occlusion.
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