Evidence map›Paper›PMID 41823989›Full record

ArticleeLife2026

Spatially targeted inhibitory rhythms differentially affect neuronal integration.

Drew B Headley, Benjamin Latimer, Adin Aberbach, Satish S Nair

Abstract read
In one paragraph

Article in eLife, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Delayed Accumulation of Inhibitory Input Explains Gamma Frequency Variation with Changing Contrast in an Inhibition Stabilized Network.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Drew B Headley *Center for Molecular and Behavioral Neuroscience, Rutgers University - Newark, Newark, United States.ORCID https://orcid.org/0000-0003-0243-3363
Benjamin Latimer *Electrical Engineering and Computer Science, University of Missouri, Columbia, United States.
Adin AberbachElectrical Engineering and Computer Science, University of Missouri, Columbia, United States.
Satish S NairElectrical Engineering and Computer Science, University of Missouri, Columbia, United States.ORCID https://orcid.org/0000-0002-1489-7029

Funding

CRCNS: Optimization of closed-loop control of gamma oscillationsR01MH122023 · NIMH · UNIVERSITY OF MISSOURI-COLUMBIA · PI NAIR, SATISH S · 2019 to 2023
$1.4M
National Science Foundation OAC-1730655NIH HHS MH122023NIH HHS NINDS 5R01NS123396NIMH NIH HHS R01 MH122023
6 · The paper itself

Abstract

Pyramidal neurons form dense recurrently connected networks with multiple types of inhibitory interneurons. A major differentiator between interneuron subtypes is whether they synapse onto perisomatic or dendritic regions. They can also engender local inhibitory rhythms, beta (12-35 Hz) and gamma (40-80 Hz). The interaction between the rhythmicity of inhibition and its spatial targeting on the neuron may determine how it regulates neuronal integration. Thus, we sought to understand how rhythmic perisomatic and distal dendritic inhibition impacted integration in a layer 5 pyramidal neuron model with realistic dendrites supporting Na

Indexed as

InterneuronsModels, NeurologicalNeural InhibitionPyramidal CellsAction PotentialsAnimalsBeta RhythmDendritesGamma RhythmNerve NetParvalbuminsSomatostatinParvalbuminsSomatostatindendritic integrationinhibitory rhythmic modulationinterneuron subtype specificityneurosciencerat

Identifiers

PMID41823989
PMCPMC12987649

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.