Evidence map›Paper›PMID 41823664›Full record

ArticleEmerging microbes & infections2026

Efficacy and immunological correlates of an mRNA-LNP vaccine for protection against an emerging rickettsial pathogen.

Mingqun Lin, Stephen Denton, Nan Duan, Naveed Iqbal, Prosper N Boyaka, Garima Dwivedi, Mohamad-Gabriel Alameh, Drew Weissman, Yasuko Rikihisa

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Emerging microbes & infections, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Mingqun LinDepartment of Veterinary Biosciences, The College of Veterinary Medicine, Infectious Diseases Institute, The Ohio State University, Columbus, OH, USA.
Stephen DentonDepartment of Veterinary Biosciences, The College of Veterinary Medicine, Infectious Diseases Institute, The Ohio State University, Columbus, OH, USA.
Nan DuanDepartment of Veterinary Biosciences, The College of Veterinary Medicine, Infectious Diseases Institute, The Ohio State University, Columbus, OH, USA.
Naveed IqbalDepartment of Veterinary Biosciences, The College of Veterinary Medicine, Infectious Diseases Institute, The Ohio State University, Columbus, OH, USA.
Prosper N BoyakaDepartment of Veterinary Biosciences, The College of Veterinary Medicine, Infectious Diseases Institute, The Ohio State University, Columbus, OH, USA.
Garima DwivediInfecitious Disease Division, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Mohamad-Gabriel AlamehDepartment of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Drew WeissmanInfecitious Disease Division, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Yasuko RikihisaDepartment of Veterinary Biosciences, The College of Veterinary Medicine, Infectious Diseases Institute, The Ohio State University, Columbus, OH, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A rickettsial pathogen,

Indexed as

Bacterial Outer Membrane ProteinsBacterial VaccinesPorinsAnimalsAntibodies, BacterialAntibodies, NeutralizingCD4-Positive T-LymphocytesCD8-Positive T-LymphocytesFemaleHumansImmunoglobulin GInterferon-gammaLiposomesMiceNanoparticlesRNA, MessengerAntibodies, BacterialAntibodies, NeutralizingBacterial Outer Membrane ProteinsBacterial VaccinesImmunoglobulin GInterferon-gammaLipid NanoparticlesLiposomesPorinsRNA, MessengerCD4+ and CD8+ T cellsEhrlichiaIFN-γIgG1/IgG2amRNA-LNPneutralizing antibodyOMP-1BRickettsia vaccine

Identifiers

PMID41823664
PMCPMC13159599

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.