Observational studyNursing in critical care2026
Sleep Quality and Delirium Occurrence in Intensive Care Unit Patients: A Prospective Observational Study.
Observational study in Nursing in critical care, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
3 citing papers in PubMed.
- Effect of the orexin receptor antagonist, suvorexant, on sleep architecture in the early postoperative period following cardiac surgery: a randomized controlled trial.Critical care (London, England) · 2026Trial
- Wearable Sleep and Circadian Monitoring in Intensive Care Nursing: A Scoping Review.Nursing in critical care · 2026Article
- Effects of a non-pharmacological multicomponent intervention on delirium, sleep quality, and total sleep time among emergency intensive care unit patients in South Korea: a non-equivalent control group time-series study.Journal of Korean biological nursing science · 2026Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
backgroundPatients in the intensive care unit (ICU) frequently experience sleep disturbances. Although circadian rhythm disruption caused by poor sleep is known to increase the risk of delirium, empirical research on this association remains limited.
aimTo investigate the association between sleep quality and the development of delirium in ICU patients. STUDY
designThis prospective observational study was conducted in six ICUs across three university hospitals in South Korea. Sleep parameters were measured using the Fitbit Sense wearable device, and delirium was assessed with the confusion assessment method for the ICU. We performed multivariable logistic regression to examine the association between sleep quality and delirium occurrence.
resultsA total of 357 non-delirious patients were included in the study. Delirium occurred in 19.3% of patients during their ICU stay. On the second day of the ICU stay, 9.3% screened positive for delirium. Shorter sleep time measured in minutes (OR = 0.997, 95% CI: 0.993-1.000, p = 0.046) and a higher wake after sleep onset ratio (OR = 1.050, 95% CI: 1.010-1.091, p = 0.014) on the first night were statistically significantly associated with delirium on the second day. On the third day, 14.9% of patients screened positive. Delirium on the third day was associated with greater disease severity (OR = 2.879, 95% CI: 1.417-5.847, p = 0.003) and the presence of delirium on the second day (OR = 262.133, 95% CI: 14.247-4823.137, p < 0.001). There was no statistically significant association between sleep parameters from the previous night and delirium on the third day.
conclusionsPoor sleep quality during the first night in the ICU-especially reduced sleep time and increased wake after sleep onset-may be linked to the development of delirium. RELEVANCE TO CLINICAL PRACTICE: Critical care nurses should closely monitor patients' sleep and consider early interventions to support circadian rhythm preservation as part of delirium prevention strategies. STUDY REGISTRATION: The study protocol was registered with the Clinical Research Information Service (https://cris.nih.go.kr); KCT0007851.
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