ArticleClinical & experimental ophthalmology2026
Femtosecond Laser Created Corneal Allogenic Intrastromal Ring Segments for Keratoconus.
Article in Clinical & experimental ophthalmology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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Who cites it
1 citing paper in PubMed.
- Visual, Tomographic, and Biomechanical Outcomes of CAIRS with Accelerated Cross-Linking in Moderate to Advanced Keratoconus: A 6-Month Retrospective Case Series.Clinical ophthalmology (Auckland, N.Z.) · 2026Article
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Authors and funding
3 authors.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundTo evaluate the clinical outcomes of femtosecond laser-created corneal allogenic intrastromal ring segments (femto-CAIRS) in keratoconic eyes using a newly described nomogram.
methodsThis retrospective case series recruited 85 eyes from 75 patients. Corrected and uncorrected visual acuity (CDVA/UDVA), refractive error, corneal topography, and higher-order aberrations were measured prior to surgery and ≥ 3 months postoperatively. All CAIRS were created using a femtosecond laser and the Brisbane nomogram was used to determine segment width, thickness, arc length, implantation axis and channel depth based on individual corneal topography.
resultsThe mean follow-up time was 7.5 ± 5.0 months; 18 eyes had prior cross-linking (CXL), 30 underwent simultaneous CXL, and 37 had no CXL. Postoperatively, UDVA improved by 0.4 logMAR (p < 0.001) and CDVA by 0.2 logMAR (p < 0.001). There was an improvement of 5 or more lines in 31 eyes (43.7%), 8 eyes (11.3%) had no change in UDVA, 1 eye lost 1 line, and 1 eye lost 2 lines. There was a significant reduction in the mean spherical equivalent, refractive astigmatism, flat K, steep K, mean K, and KMax, and an improvement in total higher order aberrations and vertical coma (all p < 0.001). Reduction in KMax was greater in eyes that underwent simultaneous CXL compared to those without CXL (-4.28D vs. -0.70D; p = 0.018). No significant complications occurred.
conclusionsFemto-CAIRS guided by the Brisbane nomogram provides a tailored treatment approach that improved visual acuity and regularisation of the central cornea. Further studies are required to validate our nomogram and clarify the effect of cross-linking on CAIRS.
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