Evidence map›Paper›PMID 41823550›Full record

Trial reportMicrobiology spectrum2026

Evaluation of contezolid's cerebrospinal fluid concentration and safety in tuberculous meningitis patients.

Mailing Huang, Yujin Wang, Tao Chen, Yu Lu, Naihui Chu, Wenjuan Nie

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Microbiology spectrum, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Mailing Huang *Department of Tuberculosis, Beijing Chest Hospital, Capital Medical University, Beijing, China.
Yujin Wang *Department of Tuberculosis, Beijing Chest Hospital, Capital Medical University, Beijing, China.
Tao ChenShanghai Institute of Infectious Disease and Biosecurity, Fudan University, Shanghai, China.
Yu LuBeijing Tuberculosis and Thoracic Tumor Institute, Beijing, China.ORCID 0000-0002-9038-1884
Naihui ChuDepartment of Tuberculosis, Beijing Chest Hospital, Capital Medical University, Beijing, China.ORCID 0000-0002-7468-1705
Wenjuan NieDepartment of Tuberculosis, Beijing Chest Hospital, Capital Medical University, Beijing, China.ORCID 0000-0003-1109-1983

Funding

Beijing Municipal Health Commission Dengfeng Program G202511062Beijing Municipal Health Commission Excellent Clinical Research Program for Research-Oriented Wards BRWEP2024W042160104 and BRWEP2024W042160109Guangzhou National Laboratory 2024 Special Project on Tuberculosis Short-Course Therapy GZNL2024A01030the Beijing Tongzhou District Science and Technology Program Project WS2024017Tongzhou District Health Development Research Reserve Program, Tongzhou District Commission of Science and Technology of Beijing Municipality of China KJ2023CX048
6 · The paper itself

Abstract

Tuberculous meningitis (TBM) is the most severe form of tuberculosis (TB) with high mortality. This study evaluated the cerebrospinal fluid (CSF) concentration and safety of the novel oxazolidinone contezolid compared to linezolid in TBM patients. In this randomized prospective study, 10 TBM patients received either a linezolid-containing (

Indexed as

Antitubercular AgentsOxazolidinonesTuberculosis, MeningealAdultAgedCerebrospinal FluidFemaleHumansLinezolidMaleMicrobial Sensitivity TestsMiddle AgedMycobacterium tuberculosisProspective StudiesAntitubercular AgentsLinezolidOxazolidinonescerebrospinal fluid concentrationcontezolidtuberculous meningitis

Identifiers

PMID41823550
PMCPMC13055287

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.