Evidence map›Paper›PMID 41823529›Full record

ArticleInternational journal of oncology2026

Therapeutic implications of targeting cancer testis antigen MAGEA1 in cervical cancer.

Ayoung Kim, Jina Kim, Woori Kwak, Kyumin Mo, Soohyun Choe, Minyeong Jeon, Jisun Lee, Jun-Won Yun, Hyunho Yoon

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Ayoung Kim *Department of Medical and Biological Sciences, The Catholic University of Korea, Bucheon, Gyeonggi 14662, Republic of Korea.
Jina Kim *Department of Medical and Biological Sciences, The Catholic University of Korea, Bucheon, Gyeonggi 14662, Republic of Korea.
Woori Kwak *Department of Medical and Biological Sciences, The Catholic University of Korea, Bucheon, Gyeonggi 14662, Republic of Korea.
Kyumin MoDepartment of Medical and Biological Sciences, The Catholic University of Korea, Bucheon, Gyeonggi 14662, Republic of Korea.
Soohyun ChoeDepartment of Medical and Biological Sciences, The Catholic University of Korea, Bucheon, Gyeonggi 14662, Republic of Korea.
Minyeong JeonDepartment of Medical and Biological Sciences, The Catholic University of Korea, Bucheon, Gyeonggi 14662, Republic of Korea.
Jisun LeeDepartment of Medical and Biological Sciences, The Catholic University of Korea, Bucheon, Gyeonggi 14662, Republic of Korea.
Jun-Won YunLaboratory of Veterinary Toxicology, College of Veterinary Medicine and Research Institute for Veterinary Science, Seoul National University, Seoul 08826, Republic of Korea.
Hyunho YoonDepartment of Medical and Biological Sciences, The Catholic University of Korea, Bucheon, Gyeonggi 14662, Republic of Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

MAGE family member A1 (MAGEA1), a cancer‑testis antigen (CTA), is aberrantly expressed in several malignancies such as lung and liver cancers. However, its role in cervical cancer remains to be elucidated. The present study investigated the functional significance and therapeutic potential of MAGEA1 in cervical cancer using lentiviral short hairpin RNA‑mediated knockdown, a series of functional assays, RNA sequencing (RNA‑seq), and nude mouse xenograft models. It was found that MAGEA1 was upregulated in cervical cancer cells and its knockdown substantially suppressed cell proliferation, migration, invasion, and

Indexed as

Antigens, NeoplasmBiomarkers, TumorMelanoma-Specific AntigensUterine Cervical NeoplasmsAnimalsApoptosisCell Line, TumorCell MovementCell ProliferationDrug Resistance, NeoplasmFemaleGene Expression Regulation, NeoplasticGene Knockdown TechniquesHumansMiceMice, NudeAntigens, NeoplasmBiomarkers, TumorMAGEA1 protein, humanMelanoma-Specific AntigensRNA, Small Interferingbiomarkercancer testis antigencervical cancerMAGE family member A1oncogene

Identifiers

PMID41823529
PMCPMC13004431

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.