Evidence map›Paper›PMID 41823525›Full record

ReviewOncology reports2026

Unveiling the molecular landscape: Long non-coding RNAs in neuroblastoma (Review).

Zidong Xia, Huishan Zhai, Lei Zheng, Cheng Wang

Abstract readReview
In one paragraph

Review in Oncology reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Zidong XiaDepartment of Pediatric Surgery, Affiliated Hospital of North Sichuan Medical College, Nanchong, Sichuan 637000, P.R. China.
Huishan ZhaiDepartment of Pediatric Surgery, Affiliated Hospital of North Sichuan Medical College, Nanchong, Sichuan 637000, P.R. China.
Lei ZhengDepartment of Pediatric Surgery, Affiliated Hospital of North Sichuan Medical College, Nanchong, Sichuan 637000, P.R. China.
Cheng WangDepartment of Pediatric Surgery, Affiliated Hospital of North Sichuan Medical College, Nanchong, Sichuan 637000, P.R. China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neuroblastoma (NB) is a prevalent malignant tumor in pediatric populations, accounting for 10-15% of childhood cancer-related deaths. Standard treatments include surgery, radiotherapy and chemotherapy; however, in recent years, immunotherapy and targeted therapies have also demonstrated encouraging outcomes, particularly for high-risk NB cases. Despite these advances, more than one-third of patients either fail to respond to immunotherapy or eventually develop therapeutic resistance, highlighting the need to further explore the molecular mechanisms driving NB and to develop novel therapeutic approaches. Notably, dysregulated long non-coding RNA (lncRNA) expression is closely associated with NB prognosis, early diagnosis and therapeutic responsiveness. The present review systematically summarizes the molecular mechanisms by which lncRNAs contribute to NB development and progression, and provides an updated overview of their emerging clinical applications as diagnostic, prognostic and therapeutic targets. The current study may offer valuable insights into the future development of lncRNA-based precision diagnostic and therapeutic strategies for NB.

Indexed as

Biomarkers, TumorNeuroblastomaRNA, Long NoncodingGene Expression Regulation, NeoplasticHumansMolecular Targeted TherapyPrognosisBiomarkers, TumorRNA, Long Noncodingbiomarkerslong non-coding RNAsneuroblastomatargeted therapy

Identifiers

PMID41823525
PMCPMC13001146

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.