Evidence map›Paper›PMID 41823491›Full record

ArticleThe journal of extra-corporeal technology2026

Initiating cardiopulmonary bypass using a dry venous line: implications and analysis.

Tristan Benedict, Robert Brownlee, Christopher Foley, Nathan Hoyer, Laura Dell'Aiera, Mary Dooley, Dave Fitzgerald

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Article in The journal of extra-corporeal technology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Tristan BenedictMedical University of South Carolina, College of Health Professions, 179 Ashley Ave., Charleston, SC 29425, USA.
Robert BrownleeMedical University of South Carolina, College of Health Professions, 179 Ashley Ave., Charleston, SC 29425, USA.
Christopher FoleyMedical University of South Carolina, College of Health Professions, 179 Ashley Ave., Charleston, SC 29425, USA.
Nathan HoyerMedical University of South Carolina, College of Health Professions, 179 Ashley Ave., Charleston, SC 29425, USA.
Laura Dell'AieraMedical University of South Carolina, College of Health Professions, 179 Ashley Ave., Charleston, SC 29425, USA.ORCID 0009-0007-1934-3467
Mary DooleyMedical University of South Carolina, College of Health Professions, 179 Ashley Ave., Charleston, SC 29425, USA.
Dave FitzgeraldMedical University of South Carolina, College of Health Professions, 179 Ashley Ave., Charleston, SC 29425, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAutologous priming of the cardiopulmonary bypass (CPB) circuit is a critical technique for reducing hemodilution during cardiac surgery. Vacuum-assisted venous drainage (VAVD) offers access to an alternative method using a dry venous line, aiming to reduce hemodilution associated with crystalloid priming.

methodsThis study investigates the impact of initiating CPB with a dry venous line on gaseous microemboli (GME) production, compared to a traditional primed venous line in an adult CPB circuit. Using a controlled experimental setup with an oxygenator featuring an integrated arterial filter, we examined GME counts and sizes throughout the circuit under varying VAVD pressures and initiation techniques.

resultsResults show that higher VAVD pressures and the immediate initiation of CPB correlate with increased GME production post-oxygenator. Statistical analysis reveals significant differences in GME counts and sizes between control and experimental groups.

conclusionThe statistical differences in GME size and count observed between initiation types and pressures emphasize the importance of optimal CPB initiation strategies to minimize GME transmission. These findings underscore the need for further research to refine CPB techniques and enhance patient safety in cardiac surgery.

Indexed as

Cardiopulmonary BypassEmbolism, AirEquipment DesignHumansCardiopulmonary bypassDry venous lineGaseous microemboliInitiationVacuum-assisted venous drainageVAVD

Identifiers

PMID41823491
PMCPMC12984041

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.