Evidence map›Paper›PMID 41823344›Full record

ArticleJournal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism2026

High-temporal resolution metabolic connectivity resolved by component-based noise correction.

Murray B Reed, Samantha Graf, Matej Murgaš, Benjamin Eggerstorfer, Christian Milz, Leo R Silberbauer, Pia Falb, Elisa Briem, Alexandra Mayerweg, Gabriel Schlosser and 7 more

Abstract read
In one paragraph

Article in Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Murray B ReedDepartment of Psychiatry and Psychotherapy, Medical University of Vienna, Vienna, Austria.ORCID 0000-0002-4873-608X
Samantha GrafDepartment of Psychiatry and Psychotherapy, Medical University of Vienna, Vienna, Austria.
Matej MurgašDepartment of Psychiatry and Psychotherapy, Medical University of Vienna, Vienna, Austria.
Benjamin EggerstorferDepartment of Psychiatry and Psychotherapy, Medical University of Vienna, Vienna, Austria.ORCID 0000-0002-3400-2181
Christian MilzDepartment of Psychiatry and Psychotherapy, Medical University of Vienna, Vienna, Austria.ORCID 0000-0002-1347-0744
Leo R SilberbauerDepartment of Psychiatry and Psychotherapy, Medical University of Vienna, Vienna, Austria.
Pia FalbDepartment of Psychiatry and Psychotherapy, Medical University of Vienna, Vienna, Austria.ORCID 0000-0003-4817-3499
Elisa BriemDepartment of Psychiatry and Psychotherapy, Medical University of Vienna, Vienna, Austria.ORCID 0009-0007-4311-4031
Alexandra MayerwegDepartment of Psychiatry and Psychotherapy, Medical University of Vienna, Vienna, Austria.
Gabriel SchlosserDepartment of Psychiatry and Psychotherapy, Medical University of Vienna, Vienna, Austria.ORCID 0009-0001-0183-1100
Sebastian KlugDepartment of Psychiatry and Psychotherapy, Medical University of Vienna, Vienna, Austria.ORCID 0000-0001-8714-6608
Lukas NicsDivision of Nuclear Medicine, Department of Biomedical Imaging and Image-Guided Therapy, Medical University of Vienna, Vienna, Austria.
Godber M GodbersenDepartment of Psychiatry and Psychotherapy, Medical University of Vienna, Vienna, Austria.
Sazan RasulDivision of Nuclear Medicine, Department of Biomedical Imaging and Image-Guided Therapy, Medical University of Vienna, Vienna, Austria.
Marcus HackerDivision of Nuclear Medicine, Department of Biomedical Imaging and Image-Guided Therapy, Medical University of Vienna, Vienna, Austria.
Andreas HahnDepartment of Psychiatry and Psychotherapy, Medical University of Vienna, Vienna, Austria.ORCID 0000-0001-9727-7580
Rupert LanzenbergerDepartment of Psychiatry and Psychotherapy, Medical University of Vienna, Vienna, Austria.ORCID 0000-0003-4641-9539

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recent advances in functional PET (fPET) enable modeling of metabolic processes with second-level temporal resolution, opening applications such as imaging molecular connectivity comparable to fMRI. However, high-temporal fPET is more noise-sensitive, making meaningful signal extraction challenging. We developed a component-based preprocessing method adapted from fMRI, which models structured noise with tissue-specific regressors and removes low-frequency uptake trends (CompCor). This approach was applied to 20 high-temporal [

Indexed as

[18F]FDG[18F]fludeoxyglucoseband-passMolecular connectivitywithin-subject connectivity

Identifiers

PMID41823344
PMCPMC12987741

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.