Evidence map›Paper›PMID 41822984›Full record

ArticleEuro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin2026

Population immunity, post-vaccine and post-infection antibody responses to influenza A (H3N2) subclade J.2 and K (J.2.4.1) viruses, Hong Kong, 2025.

Samuel Ms Cheng, Nancy Hl Leung, Eunice Y Shiu, Ricky Wk Wong, Niki Ym Au, Xiaotong Huang, Natalie Km Kwok, Coco Hc Chan, John Kc Li, Leo Ch Tsang and 5 more

Abstract read
In one paragraph

Article in Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Samuel Ms ChengSchool of Public Health, The University of Hong Kong, Hong Kong Special Administrative Region, China.
Nancy Hl LeungSchool of Public Health, The University of Hong Kong, Hong Kong Special Administrative Region, China.
Eunice Y ShiuSchool of Public Health, The University of Hong Kong, Hong Kong Special Administrative Region, China.
Ricky Wk WongSchool of Public Health, The University of Hong Kong, Hong Kong Special Administrative Region, China.
Niki Ym AuSchool of Public Health, The University of Hong Kong, Hong Kong Special Administrative Region, China.
Xiaotong HuangSchool of Public Health, The University of Hong Kong, Hong Kong Special Administrative Region, China.
Natalie Km KwokSchool of Public Health, The University of Hong Kong, Hong Kong Special Administrative Region, China.
Coco Hc ChanSchool of Public Health, The University of Hong Kong, Hong Kong Special Administrative Region, China.
John Kc LiSchool of Public Health, The University of Hong Kong, Hong Kong Special Administrative Region, China.
Leo Ch TsangSchool of Public Health, The University of Hong Kong, Hong Kong Special Administrative Region, China.
Tsz Chun KwanSchool of Public Health, The University of Hong Kong, Hong Kong Special Administrative Region, China.
Tim K TsangSchool of Public Health, The University of Hong Kong, Hong Kong Special Administrative Region, China.
Leo Lm PoonSchool of Public Health, The University of Hong Kong, Hong Kong Special Administrative Region, China.
Benjamin J CowlingSchool of Public Health, The University of Hong Kong, Hong Kong Special Administrative Region, China.
Malik PeirisSchool of Public Health, The University of Hong Kong, Hong Kong Special Administrative Region, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We assessed haemagglutination inhibition (HAI) antibody titres against 2025 influenza A(H3N2) J.2 vaccine reference viruses and the novel subclade K (J.2.4.1) in age-stratified Hong Kong sera (collected May-July 2025), vaccine recipients and sera from virologically confirmed subclade J.2.2 or K infections. In contrast to mono-specific ferret sera, human sera with high J.2 HAI titres cross-reacted strongly with subclade K. Recombinant haemagglutinin- or egg-based standard dose J.2 A(H3N2) vaccines boosted geometric mean titres to K virus 5.6-fold and 2.6-fold, respectively.

Indexed as

Antibodies, ViralInfluenza A Virus, H3N2 SubtypeInfluenza, HumanInfluenza VaccinesAdolescentAdultAgedAnimalsAntibody FormationChildChild, PreschoolCross ReactionsFemaleFerretsHemagglutination Inhibition TestsHong KongAntibodies, ViralInfluenza Vaccinescross-reactioninfectioninfluenza Apopulation immunityserologysubclade Kvaccines

Identifiers

PMID41822984
PMCPMC13074472

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.