Evidence map›Paper›PMID 41822890›Full record

ArticleFrontiers in medicine2026

Prioritizing vaginal hysterectomy: a stepped algorithm with vNOTES support for benign indications.

Sezin Eda Karsli, Yusuf Ziya Kizildemir, Sibel Sak, Muhammed Erdal Sak, Hacer Uyanikoglu, Mehmet Incebiyik, Helin Kalir, Işil Işik Okuyan, Merve Civelek, Cagri Kutlugun Emral and 1 more

Abstract read
In one paragraph

Article in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Sezin Eda KarsliDepartment of Obstetrics and Gynecology, Şanlıurfa Training and Research Hospital, Şanlıurfa, Türkiye.
Yusuf Ziya KizildemirDepartment of Obstetrics and Gynecology, Faculty of Medicine, Harran University, Şanlıurfa, Türkiye.
Sibel SakDepartment of Obstetrics and Gynecology, Faculty of Medicine, Harran University, Şanlıurfa, Türkiye.
Muhammed Erdal SakDepartment of Obstetrics and Gynecology, Faculty of Medicine, Harran University, Şanlıurfa, Türkiye.
Hacer UyanikogluDepartment of Obstetrics and Gynecology, Faculty of Medicine, Harran University, Şanlıurfa, Türkiye.
Mehmet IncebiyikDepartment of Obstetrics and Gynecology, Faculty of Medicine, Harran University, Şanlıurfa, Türkiye.
Helin KalirDepartment of Nursing, Institute of Health Sciences, Harran University, Şanlıurfa, Türkiye.
Işil Işik OkuyanDepartment of Obstetrics and Gynecology, Şanlıurfa Training and Research Hospital, Şanlıurfa, Türkiye.
Merve CivelekDepartment of Obstetrics and Gynecology, Şanlıurfa Training and Research Hospital, Şanlıurfa, Türkiye.
Cagri Kutlugun EmralDepartment of Obstetrics and Gynecology, Şanlıurfa Training and Research Hospital, Şanlıurfa, Türkiye.
Bekir KahveciDepartment of Obstetrics and Gynecology, Şanlıurfa Training and Research Hospital, Şanlıurfa, Türkiye.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: This prospective study aimed to evaluate the clinical outcomes of a standardized surgical algorithm adopting a "vaginal-first" approach in patients with non-descensus uteri. It sought to redefine vNOTES as an "educational bridge" and a "safety valve" within this framework. Materials and methods: This single-center, prospective cohort study included 165 consecutive patients scheduled for hysterectomy for benign indications. A standardized stepwise algorithm was implemented: pure vaginal hysterectomy (VH) as the primary target; transition to vNOTES (second tier) in case of failure to progress; and laparoscopy or laparotomy as a final resort. All procedures were performed by a single surgeon. Results: Vaginal completion without abdominal incision was achieved in 157 patients (95.2%). Pure VH was successful in 87.9% ( Conclusion: A "vaginal-first" approach should be the standard of care for non-descensus uteri. vNOTES functions not just as a routine method, but as an educational catalyst that enhances surgical proficiency and a critical safety valve that prevents abdominal conversion. This stepped approach optimizes resource utilization while maximizing minimally invasive benefits.

Indexed as

conversion to laparoscopyminimally invasive surgerynon-descensus uterussurgical algorithmvaginal hysterectomyvNOTES

Identifiers

PMID41822890
PMCPMC12975972

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.