ArticleFrontiers in medicine2026
Factors associated with 25-year kidney allograft survival: a single-center retrospective analysis.
Article in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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4 authors.
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Abstract
Introduction: One-year outcomes after kidney transplantation (KTx) have improved markedly; however, ultra-long graft survival remains rare. We analyzed an outcome-defined sample from a single-center, single-era cohort to identify early, potentially modifiable factors associated with ≥25-year graft survival and to translate these associations into pragmatic, hypothesis-generating, center-level process targets. Methods: We retrospectively reviewed the first adult solitary KTx performed in 1980-1995. Two outcome-defined, unmatched groups were compared: ultra-long survivors (ULS; graft survival ≥25 years; Results: Cold ischemia time (CIT) was shorter in ULS than in EGF (1281.8 ± 473.9 vs. 1764.8 ± 564.9 min; Discussion: Overall, CIT showed the most consistent and potentially actionable association with long-term outcomes in this historical cohort; however, inferences are observational, and residual confounding cannot be excluded.
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