Evidence map›Paper›PMID 41822861›Full record

ArticleJournal of reproduction & infertility2025

The Effect of hCG Supplementation on Embryo Quality after Rescue

Novita Prasetiawati, Ayu Mulia Sundari, Agus Supriyadi, Hadi Sjarbaini, Tarigan Sudirmanto, Gde Suardana, Mohammad Haekal, Gangsar Pariyanti, Deana Rosaria Indah, Mulyoto Pangestu and 1 more

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Article in Journal of reproduction & infertility, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Novita PrasetiawatiDepartment of Biology, Faculty of Mathematics and Natural Sciences, Universitas Indonesia, Depok, Indonesia.
Ayu Mulia SundariCellular and Molecular Mechanisms in Biological System (CEMBIOS) Research Group, Department of Biology, Faculty of Mathematics and Natural Sciences, Universitas Indonesia, Depok, Indonesia.
Agus SupriyadiMelati Clinic, Harapan Kita Women and Children Hospital, Jakarta, Indonesia.
Hadi SjarbainiMelati Clinic, Harapan Kita Women and Children Hospital, Jakarta, Indonesia.
Tarigan SudirmantoMelati Clinic, Harapan Kita Women and Children Hospital, Jakarta, Indonesia.
Gde SuardanaMelati Clinic, Harapan Kita Women and Children Hospital, Jakarta, Indonesia.
Mohammad HaekalMelati Clinic, Harapan Kita Women and Children Hospital, Jakarta, Indonesia.
Gangsar PariyantiMelati Clinic, Harapan Kita Women and Children Hospital, Jakarta, Indonesia.
Deana Rosaria IndahMelati Clinic, Harapan Kita Women and Children Hospital, Jakarta, Indonesia.
Mulyoto PangestuDepartment of Obstetrics and Gynecology, School of Clinical Sciences, Monash University, Victoria, Australia.
Anom BowolaksonoDepartment of Biology, Faculty of Mathematics and Natural Sciences, Universitas Indonesia, Depok, Indonesia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The supplementation of human chorionic gonadotropin (hCG) into culture medium in rescue Methods: A total of 152 immature oocytes consisting of germinal vesicles (GV) and metaphase I (MI) were collected and classified into 1) control group (n=73; GV=22, MI=51) cultured in culture medium only, and 2) experimental group (n=79; GV= 23, MI=56) cultured in culture medium supplemented with 0.5 Results: After 24 Conclusion: Our study suggests that hCG supplementation into the culture medium during r-IVM does not affect embryo quality but improves the fertilization rate. Further research is needed to scrutinize the role of hCG in fertilization.

Indexed as

EmbryoHuman chorionic gonadotropinOocytesRescue IVM

Identifiers

PMID41822861
PMCPMC12977024

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