Evidence map›Paper›PMID 41822811›Full record

ArticleCurrent opinion in physiology2026

The Role of Complement and CD4 T Cells in Preeclampsia and Offspring Neurodevelopment.

Jean F Regal, Courtney A O'Kane, Sabrina M Scroggins

Abstract read
In one paragraph

Article in Current opinion in physiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Jean F RegalDepartment of Biomedical Sciences, University of Minnesota Medical School, Duluth Campus, 1035 University Dr, Duluth, MN 55812 USA.
Courtney A O'KaneDepartment of Biomedical Sciences, University of Minnesota Medical School, Duluth Campus, 1035 University Dr, Duluth, MN 55812 USA.
Sabrina M ScrogginsDepartment of Biomedical Sciences, University of Minnesota Medical School, Duluth Campus, 1035 University Dr, Duluth, MN 55812 USA.

Funding

University of Minnesota Clinical and Translational Science Institute (UMN CTSI)UL1TR002494 · NCATS · UNIVERSITY OF MINNESOTA · PI BLAZAR, BRUCE R, WEISDORF, DANIEL J · 2018 to 2022
$34.9M
University of Minnesota Clinical and Translational Science Institute (UMN CTSI)UM1TR004405 · NCATS · UNIVERSITY OF MINNESOTA · PI Bruce R Blazar, Damien A Fair · 2023 to 2026
$30.8M
Testing the efficacy of regulatory dendritic cell treatment in the prevention of preeclampsiaK01HL155240 · NHLBI · UNIVERSITY OF MINNESOTA · PI SCROGGINS, SABRINA MARIE · 2021 to 2025
$751k
NCATS NIH HHS UL1 TR002494NCATS NIH HHS UM1 TR004405NHLBI NIH HHS K01 HL155240
6 · The paper itself

Abstract

Preeclampsia is a multifactorial hypertensive disorder of pregnancy. Dysregulated innate complement activity and skewing of adaptive CD4+ T helper (T

Indexed as

complementneurodevelopmentPreeclampsiaT cells

Identifiers

PMID41822811
PMCPMC12978695

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.