Evidence map›Paper›PMID 41822758›Full record

ArticleFrontiers in genetics2026

Low-dose X-Ray induced genetic damage in human peripheral blood lymphocytes.

Laura Camila Villalba-Rondón, Laura Vélez-Lemus, William Jaramillo-Garzón, Martín Pulido-Medellín, Nelson Rangel, Milena Rondón-Lagos

Abstract read
In one paragraph

Article in Frontiers in genetics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Laura Camila Villalba-RondónEscuela de Ciencias Biológicas, Universidad Pedagógica y Tecnológica de Colombia, Tunja, Colombia.
Laura Vélez-LemusEscuela de Ciencias Biológicas, Universidad Pedagógica y Tecnológica de Colombia, Tunja, Colombia.
William Jaramillo-GarzónGrupo de Física Médica, Universidad Nacional de Colombia, Bogotá, Colombia.
Martín Pulido-MedellínGrupo de Investigación en Medicina Veterinaria y Zootecnia (GIDIMEVETZ), Universidad Pedagógica y Tecnológica de Colombia, Tunja, Colombia.
Nelson RangelDepartamento de Nutrición y Bioquímica, Facultad de Ciencias, Pontificia Universidad Javeriana, Bogotá, Colombia.
Milena Rondón-LagosEscuela de Ciencias Biológicas, Universidad Pedagógica y Tecnológica de Colombia, Tunja, Colombia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

X-rays (XR) are electromagnetic waves capable of inducing significant biological effects in living organisms. Although widely used in medicine and industry, the impact of low-dose XR exposure on human health remains insufficiently characterized. XR can generate direct and indirect DNA damage such as single- and double-strand breaks, base modifications, and DNA-protein crosslinks, leading to chromosomal alterations that disrupt cellular homeostasis and may contribute to disease development. Although previous studies have reported general increases in cytogenetic damage at low exposures, they seldom provide detailed descriptions of which chromosomes are most affected, which structural or numerical alterations predominate, or how frequently each alteration occurs. This study aimed to characterize the type and frequency of chromosomal alterations and the spectrum of genetic damage, including both clonal and non-clonal alterations, in human lymphocytes exposed

Indexed as

chromosomal abnormalitiesgenotoxicitylow-dose radiationmicronucleix-rays

Identifiers

PMID41822758
PMCPMC12975425

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.