Evidence map›Paper›PMID 41822669›Full record

ArticleCureus2026

Management of Ischemia and Necrosis Following Nonsurgical Rhinoplasty With Hyaluronic Acid: A Case Report.

Andrea Tedesco, Anna Clara C Commanducci Silva, Roberta G Neves, Ithala L Oliveira Parpinelli, Francine F Posser Ribeiro, Sabrina C Pacheco, Alan Ferreira, Antony P Barbosa

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Andrea TedescoDental Clinic, Faculty of Dentistry, Federal University of Rio de Janeiro, Rio de Janeiro, BRA.
Anna Clara C Commanducci SilvaResearch and Development, Antony Barbosa Institute, Belo Horizonte, BRA.
Roberta G NevesResearch and Development, Antony Barbosa Institute, Belo Horizonte, BRA.
Ithala L Oliveira ParpinelliPrivate Practice, Andrea Tedesco Institute, Rio de Janeiro, BRA.
Francine F Posser RibeiroPrivate Practice, Andrea Tedesco Institute, Rio de Janeiro, BRA.
Sabrina C PachecoPrivate Practice, Andrea Tedesco Institute, Rio de Janeiro, BRA.
Alan FerreiraResearch and Development, Antony Barbosa Institute, Belo Horizonte, BRA.
Antony P BarbosaPharmacy, Pontifical Catholic University of Minas Gerais, Belo Horizonte, BRA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nonsurgical rhinoplasty with hyaluronic acid (HA) is minimally invasive but may result in severe vascular complications such as ischemia and necrosis. This case report describes a 30-year-old female patient who developed ischemia and early necrosis of the nasal tip after HA injection. Treatment was initiated approximately 72 hours after the injection, and management included multipoint hyaluronidase, massage and warm compresses, low-level red laser therapy, systemic antibiotic and corticosteroid administration, in addition to hyperbaric oxygen therapy and photodynamic therapy. Regression of ischemia was observed on the first day after treatment initiation, and complete re-epithelialization occurred within 26 days. Early diagnosis and multimodal management centered on hyaluronidase favored ischemia reversal and wound healing, minimizing sequelae.

Indexed as

hyaluronic acidhyaluronidaseischemianecrosisnonsurgical rhinoplasty

Identifiers

PMID41822669
PMCPMC12978417

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.