Evidence map›Paper›PMID 41822617›Full record

ArticleCureus2026

High-Risk Human Papillomavirus and Other Sexually Transmitted Infections Among Women Living With Human Immunodeficiency Virus in Jos, Nigeria.

Nanma T Cosmas, Francis A Magaji, Shedrach Y Acheng, Lipigwe Lauya, Mark O Okolo, Elizabeth N Christian, Robert L Murphy, Lifang Hou, Chad J Achenbach, Jonah Musa

Abstract read
In one paragraph

Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Nanma T CosmasDepartment of Medical Microbiology, College of Health Sciences, University of Jos, Jos, NGA.
Francis A MagajiDepartment of Obstetrics and Gynecology, University of Jos/Jos University Teaching Hospital, Jos, NGA.
Shedrach Y AchengGenomics and Postgraduate Research Laboratory, College of Health Sciences, University of Jos, Jos, NGA.
Lipigwe LauyaDivision of Human Virology, Miradi Ltd, Jos, NGA.
Mark O OkoloDepartment of Medical Microbiology, University of Jos/Jos University Teaching Hospital, Jos, NGA.
Elizabeth N ChristianRobert J. Havey MD Institute for Global Health, Northwestern University Feinberg School of Medicine, Chicago, USA.
Robert L MurphyRobert J. Havey MD Institute for Global Health, Northwestern University Feinberg School of Medicine, Chicago, USA.
Lifang HouCenter for Global Oncology, Institute for Global Health, Northwestern University Feinberg School of Medicine, Chicago, USA.
Chad J AchenbachDepartment of Medicine, Northwestern University Feinberg School of Medicine, Chicago, USA.
Jonah MusaDepartment of Obstetrics and Gynecology, University of Jos/Jos University Teaching Hospital, Jos, NGA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background Women living with human immunodeficiency virus (WLWH) have a higher risk of acquiring human papillomavirus (HPV) and other sexually transmitted infections (STIs) due to their compromised immune systems. The presence of HPV, HIV, and other STIs has been implicated in cervical carcinogenesis. This study sought to understand and estimate the association between HPV infection and other STIs among HIV-positive women with and without cervical precancer. Methodology This study looked at women living with HIV who had been diagnosed with either low- or high-grade squamous intraepithelial lesions. This study was a part of the U54 cervical cancer project in Jos, Nigeria, from August 2019 to January 2022. Cervical swab samples were used for DNA extraction and genotyping using the HPV 28 Anyplex II (Seegene). To identify seven of the most common STIs, we used the Allplex™ STI Essential Assay (Seegene) and the Allplex™ Genital Ulcer Assay (Seegene) for seven ulcer-causing microbes. Results In total, 101 women were included in this study. The median age of the participants was 50 years (interquartile range = 43-57). The overall HPV prevalence was 65.3% (66/101). Among these, hrHPV infection occurred in 40.0% of the women in the age group of <40 years and 31.0% in the age group of ≥40 years. Approximately 40% of hrHPV-positive women were co-infected with at least one STI (p = 0.006). Having multiple STIs was associated with hrHPV infection (p = 0.019 for multiple essential STIs and p = 0.007 for multiple genital ulcers causing STIs). On univariate analysis, we found hrHPV to be associated at 95% confidence interval with any essential STI (p = 0.008), a single STI (p = 0.016), any genital ulcer microbe (p = 0.003), herpes simplex virus 1 (p = 0.043),

Indexed as

essential stisgenital ulcers causing stishiv-positive womenhrhpv infectionjosnigeria

Identifiers

PMID41822617
PMCPMC12978686

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.