Evidence map›Paper›PMID 41822591›Full record

ArticleVeterinary world2026

Dietary

Shouzhen Liu, Qianmei Zhang, Yunhe Wang, Wenqing Zhu, Lanxin Li, Yong Zhang, Jing Zhang

Abstract read
In one paragraph

Article in Veterinary world, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Shouzhen LiuCollege of Veterinary Medicine, Gansu Agricultural University, Lanzhou city, Gansu Province, P. R. China.
Qianmei ZhangInstitute of Laboratory Animal Science, Guizhou University of Traditional Chinese Medicine, Guiyang City, Guizhou Province, P. R. China.
Yunhe WangInstitute of Laboratory Animal Science, Guizhou University of Traditional Chinese Medicine, Guiyang City, Guizhou Province, P. R. China.
Wenqing ZhuInstitute of Laboratory Animal Science, Guizhou University of Traditional Chinese Medicine, Guiyang City, Guizhou Province, P. R. China.
Lanxin LiInstitute of Laboratory Animal Science, Guizhou University of Traditional Chinese Medicine, Guiyang City, Guizhou Province, P. R. China.
Yong ZhangCollege of Veterinary Medicine, Gansu Agricultural University, Lanzhou city, Gansu Province, P. R. China.
Jing ZhangInstitute of Laboratory Animal Science, Guizhou University of Traditional Chinese Medicine, Guiyang City, Guizhou Province, P. R. China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and Aim: The global ban on antibiotic growth promoters in poultry production has accelerated the search for safe and effective natural alternatives. Polysaccharides derived from traditional Chinese medicinal plants have shown promise due to their antioxidant and immunomodulatory properties. This study evaluated the efficacy of dietary Materials and Methods: A total of 420 one-day-old Arbor Acre broilers were randomly assigned to five dietary treatments for 42 days, with six replicates per treatment. The treatments included an antibiotic-free basal diet (control), a basal diet supplemented with colistin sulfate and virginiamycin (antibiotics), and the basal diet supplemented with SBP at 100 mg/kg (SBP-L), 200 mg/kg (SBP-M), or 400 mg/kg (SBP-H). Growth performance parameters were recorded, and on days 21 and 42, serum and intestinal antioxidant indices, digestive enzyme activities, intestinal morphology, secretory immunoglobulin A (sIgA) levels, and the expression of immune-related genes (C-C motif chemokine ligand 28 [CCL28], A proliferation-inducing ligand (tumor necrosis factor ligand superfamily member 13) [APRIL]) and toll-like receptor 4 protein were evaluated. Results: Dietary SBP supplementation significantly improved average daily gain (ADG) and feed conversion ratio during the starter phase without affecting feed intake or mortality (p < 0.05). Over the entire 42-day period, broilers fed 400 mg/kg SBP showed a 3.4% higher ADG than those receiving antibiotics (p < 0.05). SBP boosted systemic and intestinal antioxidant capacity by increasing glutathione peroxidase, glutathione reductase, Superoxide dismutase, and total antioxidant capacity activities while lowering malondialdehyde levels (p < 0.05). Additionally, SBP increased digestive enzyme activities, improved villus height-to-crypt depth ratios, and raised sIgA concentrations in the duodenum and jejunum. The upregulation of TLR4 protein and the immune-related genes CCL28 and APRIL indicated enhanced intestinal mucosal immunity, especially in the SBP-M and SBP-H groups. Conclusion: Dietary supplementation with

Indexed as

antibiotic alternativeantioxidant capacitybroiler chickensgrowth performancegut immunityintestinal morphologyScutellaria baicalensis polysaccharideTraditional Chinese medicine

Identifiers

PMID41822591
PMCPMC12975630

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.