Poor self-rated health in individuals with irritable bowel syndrome but no increased 10-year cardiovascular risk: results from a Swedish population-based screening program.

Introduction: Irritable bowel syndrome (IBS) has been linked to poor health, high stress and diminished quality of life. Previous findings about associations between IBS and cardiovascular disease are, however, contradictory. Our objective was to examine 10-year cardiovascular risk, lifestyle factors, and self-rated health in people with IBS compared to a reference group. Methods: Sweden's southernmost county (Scania) has implemented targeted health dialogues (THDs) in primary health care for all 40- and 50-year-olds. Before the THD, participants completed a questionnaire about their health and lifestyle. Cholesterol, blood glucose, BMI and waist-hip-ratio were measured. Participants were also invited to a research project. The present study used baseline variables from 2021 to 2024 to examine the 10-year risk of cardiovascular events according to SCORE2, four health behaviors (diet, physical activity, smoking and alcohol), and self-rated health in THD-participants with and without IBS. Analyses took into account sex, level of education and place of birth. Results: The study population comprised 8 899 (56.5%) THD participants of which 592 (6.7%) had a diagnosis of IBS. Participants with IBS did not show an increased 10-year cardiovascular risk after adjusting for confounders. However, men with IBS had higher mean diastolic blood pressure ( Conclusion: IBS was not associated with an increased 10-year cardiovascular risk in this population, but further research is needed, preferably subtype-specific. THDs and similar interventions may provide opportunities to identify needs for healthcare support in people with IBS suffering from poor self-rated health.