Evidence map›Paper›PMID 41822371›Full record

ArticleOpen forum infectious diseases2026

Emergence of Dalbavancin, Vancomycin, and Daptomycin Cross-resistance in MRSA During Long-term LVAD Suppression With Vancomycin Followed by Dalbavancin: Genomic Insights and Synergy With Cefadroxil.

Erica J Stohs, Bryan T Alexander, Paul D Fey, Melanie C L Foreman, Libin Xu, Kelsi Penewit, Adam Waalkes, Stephen J Salipante, Brian J Werth

Abstract readCase Reports
In one paragraph

Article in Open forum infectious diseases, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Erica J StohsDivision of Infectious Diseases, Department of Medicine, Creighton University Medical Center, Omaha, Nebraska, USA.ORCID https://orcid.org/0000-0002-8324-6414
Bryan T AlexanderDepartment of Pharmaceutical & Nutrition Care, Nebraska Medicine, Omaha, Nebraska, USA.ORCID https://orcid.org/0000-0001-7656-2569
Paul D FeyDepartment of Pathology, Microbiology, and Immunology, University of Nebraska Medical Center, Omaha, Nebraska, USA.ORCID https://orcid.org/0000-0003-0939-6884
Melanie C L ForemanDepartment of Pharmacy, School of Pharmacy, University of Washington, Seattle, Washington, USA.
Libin XuDepartment of Medicinal Chemistry, School of Pharmacy, University of Washington, Seattle, Washington, USA.ORCID https://orcid.org/0000-0003-1021-5200
Kelsi PenewitDepartment of Laboratory Medicine and Pathology, School of Medicine, University of Washington, Seattle, Washington, USA.ORCID https://orcid.org/0000-0003-1454-6381
Adam WaalkesDepartment of Laboratory Medicine and Pathology, School of Medicine, University of Washington, Seattle, Washington, USA.ORCID https://orcid.org/0000-0002-5202-1108
Stephen J SalipanteDepartment of Laboratory Medicine and Pathology, School of Medicine, University of Washington, Seattle, Washington, USA.ORCID https://orcid.org/0000-0001-8355-6992
Brian J WerthDepartment of Pharmacy, School of Pharmacy, University of Washington, Seattle, Washington, USA.ORCID https://orcid.org/0000-0001-6751-4098

Funding

Contribution of altered lipid metabolism to resistance to cell envelope-targeting antimicrobials in MRSAR01AI136979 · NIAID · UNIVERSITY OF WASHINGTON · PI Brian James Werth, Libin Xu · 2018 to 2026
$4.1M
NIAID NIH HHS R01 AI136979
6 · The paper itself

Abstract

We present a case in which vancomycin and dalbavancin exposure preceded emergence of nonsusceptibility to dalbavancin, vancomycin, and daptomycin in a strain of methicillin-resistant

Indexed as

chronic infectiondalbavancin resistancedaptomycin nonsusceptibledriveline infectionlipoglycopeptide cross-resistance

Identifiers

PMID41822371
PMCPMC12978522

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.