Evidence map›Paper›PMID 41822336›Full record

ArticleFrontiers in cellular and infection microbiology2026

Clinical characterization of an

Gonzalo Valenzuela, Patricia García, Juan A Ugalde, Nicolás Canales, Javiera Jiménez, Tomás Carrasco, Patricio Ross, Pamela Medina, Carolina Núñez, Aniela Wozniak

Abstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Gonzalo ValenzuelaDepartment of Pediatric Infectious Diseases and Immunology, Escuela de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile.
Patricia GarcíaRed de Salud UC CHRISTUS, Santiago, Chile.
Juan A UgaldeMillennium Initiative for Collaborative Research on Bacterial Resistance (MICROB-R), Santiago, Chile.
Nicolás CanalesMillennium Initiative for Collaborative Research on Bacterial Resistance (MICROB-R), Santiago, Chile.
Javiera JiménezDepartment of Clinical Laboratories; Laboratory of Microbiology, Escuela de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile.
Tomás CarrascoEscuela de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile.
Patricio RossRed de Salud UC CHRISTUS, Santiago, Chile.
Pamela MedinaDepartment of Pediatric Infectious Diseases and Immunology, Escuela de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile.
Carolina NúñezRed de Salud UC CHRISTUS, Santiago, Chile.
Aniela WozniakRed de Salud UC CHRISTUS, Santiago, Chile.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: In 2024, Chile experienced an outbreak of invasive group A Methods: We analyzed 2,307 GAS isolates collected between 2018 and 2024, including 2,249 noninvasive isolates and 58 iGAS isolates. Noninvasive cases were classified as outpatient niGAS or hospitalized niGAS (h-niGAS). Antimicrobial susceptibility testing was performed for all isolates. Results: Among niGAS isolates, 2,119 were obtained from outpatients and 130 from hospitalized patients. h-niGAS isolates showed the highest proportion of clindamycin resistance (42%), whereas iGAS isolates showed the lowest (16%). Notably, clindamycin resistance among iGAS increased from 0% during 2020-2023 to nearly 20% in 2024. The most frequent Discussion: These findings suggest that the Chilean outbreak was driven by the expansion of the

Indexed as

Antigens, BacterialBacterial Outer Membrane ProteinsCarrier ProteinsDisease OutbreaksStreptococcal InfectionsStreptococcus pyogenesAdolescentAdultAgedAnti-Bacterial AgentsChildChild, PreschoolChileDrug Resistance, BacterialFemaleHumansAnti-Bacterial AgentsAntigens, BacterialBacterial Outer Membrane ProteinsCarrier Proteinsstreptococcal M proteinVirulence Factorsemm typing and genomic surveillancegroup A Streptococcusinvasive infectionsM1UK lineageoutbreakvirulence factors

Identifiers

PMID41822336
PMCPMC12975739

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.