Evidence map›Paper›PMID 41822267›Full record

ArticleFrontiers in gastroenterology (Lausanne, Switzerland)2025

Living with a transplanted liver is associated with cytopenias: a nationwide cohort study.

Kajinth Manogarathaas, Nicoline S Arentoft, Jens G Hillingsø, Anne Marie R Jensen, Annette D Fialla, Gerda E Villadsen, Peter Holland-Fischer, Shoaib Afzal, Børge G Nordestgaard, Peter Brown and 2 more

Abstract read
In one paragraph

Article in Frontiers in gastroenterology (Lausanne, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Kajinth ManogarathaasDepartment of Infectious Diseases, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark.
Nicoline S ArentoftDepartment of Infectious Diseases, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark.
Jens G HillingsøDepartment of Surgery and Transplantation, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark.
Anne Marie R JensenDepartment of Infectious Diseases, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark.
Annette D FiallaDepartment of Gastroenterology, Odense University Hospital, Odense, Denmark.
Gerda E VilladsenDepartment of Hepatology and Gastroenterology, Aarhus University Hospital, Aarhus, Denmark.
Peter Holland-FischerDepartment of Gastroenterology, Aalborg University Hospital, Aalborg, Denmark.
Shoaib AfzalThe Copenhagen General Population Study, Department of Clinical Biochemistry, Copenhagen University Hospital - Herlev and Gentofte, Herlev, Denmark.
Børge G NordestgaardThe Copenhagen General Population Study, Department of Clinical Biochemistry, Copenhagen University Hospital - Herlev and Gentofte, Herlev, Denmark.
Peter BrownDepartment of Hematology, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark.
Allan RasmussenDepartment of Surgery and Transplantation, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark.
Susanne D NielsenDepartment of Infectious Diseases, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hematological abnormalities are common in liver transplant recipients, but evidence beyond the first-year post-transplantation is scarce. We aimed to evaluate hematological abnormalities in liver transplant recipients beyond the first-year post-transplantation. We included 437 liver transplant recipients and 1,744 age- and sex-matched controls from the general population. Odds for cytopenias were assessed using logistic regression analyses adjusted for age, sex, ethnicity, hs-CRP, smoking, and alcohol use. Potential transplant-related risk factors were assessed in liver transplant recipients only. The median time since transplantation was 7.8 years, and 47% had autoimmune liver disease as the indication for transplantation. Compared to controls, liver transplant recipients had a higher prevalence of anemia (24.5% vs. 3.5%), neutropenia (2.1% vs. 0.1%), lymphocytopenia (18.4% vs. 1.5%), and thrombocytopenia (19.2% vs. 2.2%). Living with a transplanted liver was independently associated with higher odds of anemia (aOR, 7.84 [95% CI: 5.04 - 12.18],

Indexed as

anemiacytopenialiver transplantationliver transplant receipientsLTXlymphocytopenianeutropeniathrombocytopenia

Identifiers

PMID41822267
PMCPMC12952440

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.