Evidence map›Paper›PMID 41822253›Full record

ArticleCureus2026

Sarcopenia Risk Identified by Strength, Assistance With Walking, Rising From a Chair, Climbing Stairs, and Falls (SARC-F) in Patients With Cirrhosis: A Real-World Cross-Sectional Study.

Noor Albusta, Ali Yusuf, Ahmed Ali

Abstract read
In one paragraph

Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Noor AlbustaInternal Medicine, Beth Israel Lahey Health, Burlington, USA.
Ali YusufMedicine, Bahrain Government Hospitals, Manama, BHR.
Ahmed AliMedicine, Bahrain Government Hospitals, Manama, BHR.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionSarcopenia is highly prevalent in patients with liver cirrhosis and is associated with increased morbidity, hospitalization, and mortality. However, routine screening is not consistently performed in clinical practice. The strength, assistance with walking, rising from a chair, climbing stairs, and falls (SARC-F) questionnaire is a simple tool that may facilitate early identification of sarcopenia risk.

methodsThis cross-sectional study included adult patients with cirrhosis attending a tertiary government hospital in Bahrain between January 1, 2024, and December 31, 2025. Sarcopenia risk was assessed using the SARC-F questionnaire, with a score ≥4 indicating high risk. Clinical and laboratory data were collected. Multivariable logistic regression was used to identify independent predictors of sarcopenia risk.

resultsA total of 362 patients were included (mean age 56.8 ± 11.9 years; 221 (61.0%) males). High sarcopenia risk (SARC-F ≥4) was identified in 129 patients (35.6%). Patients with high risk were older (60.2 vs 54.9 years, p < 0.001), had higher model for end-stage liver disease (MELD) scores (14.6 vs 11.2, p < 0.001), and more frequent ascites (75 (58.1%) vs 80 (34.5%), p < 0.001). They also had higher rates of hospitalization (55 (42.6%) vs 54 (23.3%), p < 0.001). On multivariable analysis, age (adjusted odds ratio (aOR): 1.05; 95% CI: 1.02-1.07), MELD score (aOR: 1.09; 95% CI: 1.04-1.14), and ascites (aOR: 1.87; 95% CI: 1.18-2.95) were independently associated with sarcopenia risk.

conclusionsSarcopenia risk appears to be common among patients with cirrhosis and is associated with markers of disease severity. The SARC-F questionnaire may serve as a simple screening tool to identify patients at higher risk in routine clinical practice.

Indexed as

chronic liver diseasecirrhosissarc-fsarcopeniascreening

Identifiers

PMID41822253
PMCPMC12977865

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