Evidence map›Paper›PMID 41822251›Full record

ArticleCureus2026

From Pancytopenia to Diagnosis: Visceral Leishmaniasis Identified Through Primary Care Assessment.

Francisco Oliveira, Virginia Martínez, Carla Moreira, Isabelle Carrilho, Teresa Pipa, Luís Neves, Daniela Azevedo, Ana Teresa Alves, Beatriz Garcia, José Rei

Abstract readCase Reports
In one paragraph

Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Francisco OliveiraFamily Medicine, Unidade de Saúde Familiar (USF) Lusitana, Unidade Local de Saúde Viseu Dão-Lafões, Viseu, PRT.
Virginia MartínezPathology and Laboratory Medicine, Unidade Local de Saúde Viseu Dão-Lafões, Viseu, PRT.
Carla MoreiraFamily Medicine, Unidade de Saúde Familiar (USF) Lusitana, Unidade Local de Saúde Viseu Dão-Lafões, Viseu, PRT.
Isabelle CarrilhoPathology and Laboratory Medicine, Unidade Local de Saúde Viseu Dão-Lafões, Viseu, PRT.
Teresa PipaFamily and Community Medicine, Unidade de Saúde Familiar (USF) Lusitana, Unidade Local de Saúde Viseu Dão-Lafões, Viseu, PRT.
Luís NevesFamily Medicine, Unidade de Saúde Familiar (USF) Lusitana, Unidade Local de Saúde Viseu Dão-Lafões, Viseu, PRT.
Daniela AzevedoFamily Medicine, Unidade de Saúde Familiar (USF) Lusitana, Unidade Local de Saúde Viseu Dão-Lafões, Viseu, PRT.
Ana Teresa AlvesFamily Medicine, Unidade de Saúde Familiar (USF) Lusitana, Unidade Local de Saúde Viseu Dão-Lafões, Viseu, PRT.
Beatriz GarciaFamily Medicine, Unidade de Saúde Familiar (USF) Lusitana, Unidade Local de Saúde Viseu Dão-Lafões, Viseu, PRT.
José ReiFamily Medicine, Unidade de Saúde Familiar (USF) Lusitana, Unidade Local de Saúde Viseu Dão-Lafões, Viseu, PRT.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Visceral leishmaniasis is a potentially life-threatening systemic parasitic infection caused by protozoa of the genus Leishmania and transmitted by sandflies. Although uncommon in Portugal, it should be considered in the differential diagnosis of prolonged fever associated with pancytopenia and hepatosplenomegaly, even in immunocompetent individuals. We report a case of a previously healthy young adult who initially presented to an urgent Family Medicine consultation in primary care, where pancytopenia was identified and prompted timely referral to secondary care. Diagnosis was confirmed by the detection of Leishmania amastigotes in bone marrow aspirate during haematological investigation. Treatment with liposomal amphotericin B resulted in complete clinical and laboratory recovery. This case highlights the importance of careful primary care assessment, recognition of red flags, and effective coordination between primary and secondary care in non-endemic settings.

Indexed as

family medicineliposomal amphotericin bpancytopeniaprimary medical carevisceral leishmaniasis (vl)

Identifiers

PMID41822251
PMCPMC12978848

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.