ArticleFrontiers in veterinary science2026
Dynamic muscle damage monitoring in pig crush injury: T2-weighted Dixon and 2D ultrasound applications.
Article in Frontiers in veterinary science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Crush injury (CI) involves compressive trauma causing muscle swelling, compartment syndrome, and neurological damage. We examined T2-Dixon and ultrasound for CI evaluation in pigs, integrating imaging with lab and tissue findings. Methods: Twelve 15-16-month-old Bama miniature pigs were randomly divided into three extrusion groups: Group A (4 h), Group B (8 h), and Group C (16 h), using custom equipment. Blood samples were collected at baseline (T0), decompression (T1), and 12 h (T2), 24 h (T3), and 72 h (T4) post-decompression. MRI and ultrasound were performed at each time point. At T4, pigs were euthanized, and compressed muscles underwent HE staining for pathological assessment. Results: Following decompression, Creatine Kinase (CK), Lactate dehydrogenase (LDH), and K Conclusion: This study confirmed the viability of the CI model through biochemical verification and demonstrated that T2-Dixon and ultrasound synergistically assessed muscle damage, providing a more thorough evaluation that surpasses the constraints of biochemical markers alone.
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