Evidence map›Paper›PMID 41822206›Full record

ArticleFrontiers in psychiatry2026

Network analysis of sleep quality-anxiety-depressive symptoms among patients with chronic heart failure.

Tingting Liao, Yanmei Gan, Yao Du, Wenhua Huang, Gaoye Li

Abstract read
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Article in Frontiers in psychiatry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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2citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Tingting Liao *Department of Cardiovascular Medicine, The First Affiliated Hospital of Guangxi Medical University, Nanning, China.
Yanmei Gan *Department of Cardiovascular Medicine, The First Affiliated Hospital of Guangxi Medical University, Nanning, China.
Yao DuDepartment of Cardiovascular Medicine, The First Affiliated Hospital of Guangxi Medical University, Nanning, China.
Wenhua HuangDepartment of Radiation Oncology, The First Affiliated Hospital of Guangxi Medical University, Nanning, China.
Gaoye LiDepartment of Cardiovascular Medicine, The First Affiliated Hospital of Guangxi Medical University, Nanning, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: While recent studies in related populations have confirmed the co-occurrence of sleep and mental symptoms in cardiac conditions, the specific network structure connecting these symptoms in a dedicated CHF cohort has not been fully elucidated. This study employed network analysis to identify central and bridging symptoms within this network. Methods: A cross-sectional study was conducted among 406 patients with chronic heart failure (CHF) at a hospital in Nanning, Guangxi, China, between August 2024 and March 2025. All participants completed a questionnaire assessing general and disease-specific characteristics. The Pittsburgh Sleep Quality Index (PSQI) was used to assess sleep quality, while anxiety and depressive symptoms were evaluated using the Hospital Anxiety and Depression Scale (HADS). A network analysis was conducted using Gaussian Graphical Models (GGM) in R software to explore the interrelationships among symptoms. Centrality indices and bridge expected influence (BEI) were used to identify central and bridge symptoms, respectively. Results: Analysis of the network centrality indicated that the HADS12 (not looking forward with enjoyment to things) and HADS13 (sudden panic) categories showed the highest centrality, with values of 1.205 and 1.208, respectively, showing their strong linkage with other symptoms and functions as central nodes in the network. Furthermore, PSQI-A (subjective sleep quality) was identified as the key bridge symptom (bridge expected influence=0.541), indicating its primary role in connecting the sleep and psychological symptom clusters. Conclusions: The identification of core and bridging symptoms in the CHF-specific symptom network underscores the potential for targeted interventions. Addressing these critical symptoms may prove beneficial in improving treatment outcomes and enhancing the quality of life for CHF patients, particularly those with comorbid anxiety and depressive symptoms.

Indexed as

anxiety and depressive symptomschronic heart failurenetwork analysissleep qualitysymptom network

Identifiers

PMID41822206
PMCPMC12975978

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