Evidence map›Paper›PMID 41822198›Full record

ArticleExperimental and therapeutic medicine2026

Identification of a novel

Chenxi Yang, Yao Xiong, Dongyang Wang, Juanzi Shi

Abstract read
In one paragraph

Article in Experimental and therapeutic medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Chenxi YangAssisted Reproduction Center, Northwest Women's and Children's Hospital, Xi'an, Shaanxi 710000, P.R. China.
Yao XiongAssisted Reproduction Center, Northwest Women's and Children's Hospital, Xi'an, Shaanxi 710000, P.R. China.
Dongyang WangTranslational Medicine Center, Northwest Women's and Children's Hospital, Xi'an, Shaanxi 710000, P.R. China.
Juanzi ShiAssisted Reproduction Center, Northwest Women's and Children's Hospital, Xi'an, Shaanxi 710000, P.R. China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Congenital disabling hearing impairment is a prevalent sensory deficit, affecting >30,000 newborns annually in China. Non-syndromic hearing loss (NSHL) accounts for a notable proportion of these cases, ~60% of which are attributed to genetic defects by heterogeneity. Although >120 genes have been linked to NSHL, a definitive molecular diagnosis remains elusive for approximately one-half of the individuals undergoing genetic testing. In the present study, a Chinese family with NSHL was investigated using next-generation sequencing of the affected members, with validation by Sanger sequencing. A novel variant was identified, namely plastin-1 (

Indexed as

intron variationnon-syndromic hearing lossPLS1RNA splicing

Identifiers

PMID41822198
PMCPMC12977184

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.